| Gene Symbol | HIST1H2BM |
|---|---|
| Entrez Gene | 8342 |
| Alt Symbol | H2B/e, H2BFE, dJ160A22.3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | histone cluster 1, H2bm |
| Other Description | H2B histone family, member E|histone 1, H2bm|histone H2B type 1-M|histone H2B.e |
| Swissprots | Q6NWQ3 Q99879 |
| Accessions | AAN06696 CAB06033 EAX03110 Q99879 BC066244 AAH66244 BC067485 AAH67485 BC067486 AAH67486 BC067487 AAH67487 BC067488 AAH67488 BC067489 AAH67489 NM_003521 NP_003512 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Subcellular Location | Nucleus. Chromosome. |
| Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
histone cluster 1, H2bm, ELISA Kit - MBS9338306 from MyBioSource
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Human HIST1H2BM ELISA Kit - E018767 from Biobool
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