Gene Symbol | HIST1H2BM |
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Entrez Gene | 8342 |
Alt Symbol | H2B/e, H2BFE, dJ160A22.3 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bm |
Other Description | H2B histone family, member E|histone 1, H2bm|histone H2B type 1-M|histone H2B.e |
Swissprots | Q6NWQ3 Q99879 |
Accessions | AAN06696 CAB06033 EAX03110 Q99879 BC066244 AAH66244 BC067485 AAH67485 BC067486 AAH67486 BC067487 AAH67487 BC067488 AAH67488 BC067489 AAH67489 NM_003521 NP_003512 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BM CRISPR/Cas9 KO Plasmid (h) - sc-411145 from Santa Cruz Biotechnology
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Histone cluster 1 H2BM HDR Plasmid (h) - sc-411145-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BM Double Nickase Plasmid (h) - sc-411145-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BM Double Nickase Plasmid (h2) - sc-411145-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BM CRISPR Activation Plasmid (h) - sc-411145-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BM CRISPR Activation Plasmid (h2) - sc-411145-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BM Lentiviral Activation Particles (h) - sc-411145-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BM Lentiviral Activation Particles (h2) - sc-411145-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BM siRNA (h) - sc-105483 from Santa Cruz Biotechnology
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Histone cluster 1 H2BM shRNA Plasmid (h) - sc-105483-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BM shRNA (h) Lentiviral Particles - sc-105483-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU112351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10080 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10080 from Sigma-Aldrich
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HIST1H2BM siRNA (Human) - CRH5462 from Cohesion Biosciences
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HIST1H2BM RNAi - H00008342-R01 from Novus Biologicals
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HIST1H2BM - MBS8230386 from MyBioSource
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shRNA set against Human HIST1H2BM (NM_003521.2) - SHH312653 from Creative biogene
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shRNA set against Human HIST1H2BM(NM_003521.2) - SHH122645 from Creative biogene
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Human HIST1H2BM siRNA - orb265964 from Biorbyt
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HIST1H2BM shRNA Plasmid (Human) - CHH5462 from Cohesion Biosciences
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HIST1H2BM miRNA 3'UTR clone - MiUTR1H-04540 from Creative biogene
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