Gene Symbol | MC2R |
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Entrez Gene | 4158 |
Alt Symbol | ACTHR |
Species | Human |
Gene Type | protein-coding |
Description | melanocortin 2 receptor (adrenocorticotropic hormone) |
Other Description | ACTH receptor|MC2 receptor|adrenocorticotropic hormone receptor|adrenocorticotropin receptor|corticotropin receptor |
Swissprots | Q504X6 Q01718 Q3MI45 A8K016 |
Accessions | AAD14989 AAO67714 BAC06130 CAA46587 EAX01503 Q01718 AK289381 BAF82070 AK315319 BAG37722 BC069074 AAH69074 BC094710 AAH94710 BC104169 AAI04170 BC104170 AAI04171 BP196054 Y10259 NM_000529 NP_000520 NM_001291911 NP_001278840 |
Function | Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). {ECO:0000269|PubMed:19329486, ECO:0000269|PubMed:20371771}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Melanocytes and corticoadrenal tissue. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
MC2-R (C-16) - sc-6876 from Santa Cruz Biotechnology
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MC2-R (H-70) - sc-13107 from Santa Cruz Biotechnology
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Anti-MC2 receptor antibody - ab77347 from Abcam
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Anti-MC2 receptor antibody - ab180793 from Abcam
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Anti-MC2 receptor antibody - ab125398 from Abcam
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Anti-MC2 receptor antibody - ab193551 from Abcam
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Anti-MC2 receptor antibody - C-terminal - ab135908 from Abcam
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297, AP) - LS-C262794 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297, PE) - LS-C262796 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa240-289) - LS-C200082 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297, FITC) - LS-C262800 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297) - LS-C329818 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (Lys289) - LS-C177192 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody - LS-C341241 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa248-297) - LS-C120630 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa9-21) - LS-C55095 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody - LS-C332326 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa261-288) - LS-C164069 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (C-Terminus) - LS-C8972 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (4th Cytoplasmic Domain) - LS-C25576 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297, APC) - LS-C262792 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa86-135) - LS-C146488 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297, Biotin) - LS-C262793 from LifeSpan Bioscience
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Anti-MC2R / ACTHR / ACTH Receptor Antibody (aa268-297, Azide-free, HRP) - LS-C262795 from LifeSpan Bioscience
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Melanocortin-2 R/MC2R Antibody - NBP1-70996 from Novus Biologicals
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