| Gene Symbol |
MC2R
|
| Entrez Gene |
4158
|
| Alt Symbol |
ACTHR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melanocortin 2 receptor (adrenocorticotropic hormone)
|
| Other Description |
ACTH receptor|MC2 receptor|adrenocorticotropic hormone receptor|adrenocorticotropin receptor|corticotropin receptor
|
| Swissprots |
Q504X6 Q01718 Q3MI45 A8K016
|
| Accessions |
AAD14989 AAO67714 BAC06130 CAA46587 EAX01503 Q01718 AK289381 BAF82070 AK315319 BAG37722 BC069074 AAH69074 BC094710 AAH94710 BC104169 AAI04170 BC104170 AAI04171 BP196054 Y10259 NM_000529 NP_000520 NM_001291911 NP_001278840
|
| Function |
Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). {ECO:0000269|PubMed:19329486, ECO:0000269|PubMed:20371771}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Melanocytes and corticoadrenal tissue.
|
| Top Pathways |
cAMP signaling pathway, Neuroactive ligand-receptor interaction
|
![Western Blot: MC2 Receptor Overexpression Lysate (Adult Normal) [NBP2-04160] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MC2 Receptor.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26147_MC2%2520Receptor%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04160-img0001.jpg)