ACE

Gene Symbol	ACE
Entrez Gene	1636
Alt Symbol	ACE1, CD143, DCP, DCP1, ICH, MVCD3
Species	Human
Gene Type	protein-coding
Description	angiotensin I converting enzyme
Other Description	CD143 antigen|angiotensin I converting enzyme (peptidyl-dipeptidase A) 1|angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript|angiotensin converting enzyme, somatic isoform|angiotensin-converting enzyme|carboxycathepsin|dipeptidyl carboxypeptidase 1|dipeptidyl carboxypeptidase I|kininase II|peptidase P|testicular ECA
Swissprots	E7EU16 B0LPF0 Q59GY8 P22966 Q7M4L4 Q53YX9 P12821 B4DXI3
Accessions	AAD28560 AAD28561 AAP03651 AAP13243 AAR03504 ABA39228 ABA39229 ABY87529 AHV83440 CAA02045 EAW94311 EAW94312 EAW94313 EAW94314 EAW94315 EAW94316 EAW94317 EAW94318 EAW94319 EAW94320 EAW94321 P12821 AB208971 BAD92208 AK296566 BAG59186 AK300516 BAG62228 AK301988 BAG63395 AK302019 BAG63418 AK309514 BM908180 BM908222 J04144 AAA51684 JQ927553 AFK65504 M26657 AAA60611 M29981 S81361 AAD14360 X16295 CAA34362 XM_005257110 XP_005257167 XM_006721737 XP_006721800 NM_000789 NP_000780 NM_001178057 NP_001171528 NM_152830 NP_690043 NM_152831
Function	Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Subcellular Location	Angiotensin-converting enzyme, soluble form: Secreted.
Tissue Specificity	Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. {ECO:0000269|PubMed:10924499, ECO:0000269|PubMed:10969042, ECO:0000269|PubMed:12459472, ECO:0000269|PubMed:15671045}.
Top Pathways	Hypertrophic cardiomyopathy (HCM), Chagas disease (American trypanosomiasis), Renin-angiotensin system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACE (CD143) Human ELISA Kit - ab119577 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 5 pg/ml Range 156 pg/ml - 10000 pg/ml

Human ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F3949 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 0.15 ng/ml Range 0.123-12 ng/ml

Rat ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F3950 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.122 ng/ml Range 0.123-12 ng/ml

Mouse ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F3951 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.135 ng/ml Range 0.123-12 ng/ml

Rabbit ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F5965 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.128 ng/ml Range 0.123-12 ng/ml

Bovine ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F5966 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 2.15 ng/ml Range 0.123-12 ng/ml

Mouse ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F2575 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 0.123-12 ng/ml

Human ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F2574 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 5 pg/ml Range 0.123-12 ng/ml

Pig ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F5827 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 11.2 pg/ml Range 0.123-12 ng/ml

Mouse ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F217 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.123 ng/ml Range 0.123-12 ng/ml

Human ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F672 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.123-12 ng/ml

Mouse ACE / CD143 ELISA Kit (Sandwich ELISA) - LS-F10727 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 0.123-12 ng/ml

Human DCP / Des-Gamma Carboxyprothrombin ELISA Kit (Sandwich ELISA) - LS-F10624 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.312-20 ng/ml

Human ACE Quantikine ELISA Kit - DACE00 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 0.051 ng/mL Range 0.8 - 50 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma, Saliva)

Human ACE DuoSet ELISA - DY929 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Mouse ACE DuoSet ELISA - DY1513 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 93.80 - 6,000 pg/mL

Quantikine Immunoassay Control Set 839 for Human ACE/CD143 - QC32 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human ACE ELISA Kit - 55R-1705 from Fitzgerald Category ELISA Kit Prices $495.00 Sizes 1 kit

ACE ELISA Kit (Human) : 96 Wells (OKAG00191) - OKAG00191 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 125 pg/mL Range 125-8,000 pg/mL

Human ACE ELISA kit - abx050001 from Abbexa Category ELISA Kit Sensitivity < 5pg/ml Range 156 pg/ml-10, 000 pg/ml

Human ACE ELISA Kit - abx150519 from Abbexa Category ELISA Kit Sensitivity 0.16 ng/ml Range 0.391 ng/ml - 25 ng/ml

Human CD143 ELISA Kit - abx056067 from Abbexa Category ELISA Kit

Angiotensin I Converting Enzyme, ACE, Human, ELISA Kit - E-EL-H0002 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

ACE I (Angiotensin I Converting Enzyme), Human, ELISA Kit - E-EL-H0246 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

ACE, Human, ELISA Kit - BEK1001 from ARP American Research Products Category ELISA Kit Prices $589.00 Sizes 96 t Sensitivity < 5pg/ml Range 156 pg/ml-10,000 pg/ml

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