ACE

Gene Symbol	ACE
Entrez Gene	1636
Alt Symbol	ACE1, CD143, DCP, DCP1, ICH, MVCD3
Species	Human
Gene Type	protein-coding
Description	angiotensin I converting enzyme
Other Description	CD143 antigen|angiotensin I converting enzyme (peptidyl-dipeptidase A) 1|angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript|angiotensin converting enzyme, somatic isoform|angiotensin-converting enzyme|carboxycathepsin|dipeptidyl carboxypeptidase 1|dipeptidyl carboxypeptidase I|kininase II|peptidase P|testicular ECA
Swissprots	E7EU16 B0LPF0 Q59GY8 P22966 Q7M4L4 Q53YX9 P12821 B4DXI3
Accessions	AAD28560 AAD28561 AAP03651 AAP13243 AAR03504 ABA39228 ABA39229 ABY87529 AHV83440 CAA02045 EAW94311 EAW94312 EAW94313 EAW94314 EAW94315 EAW94316 EAW94317 EAW94318 EAW94319 EAW94320 EAW94321 P12821 AB208971 BAD92208 AK296566 BAG59186 AK300516 BAG62228 AK301988 BAG63395 AK302019 BAG63418 AK309514 BM908180 BM908222 J04144 AAA51684 JQ927553 AFK65504 M26657 AAA60611 M29981 S81361 AAD14360 X16295 CAA34362 XM_005257110 XP_005257167 XM_006721737 XP_006721800 NM_000789 NP_000780 NM_001178057 NP_001171528 NM_152830 NP_690043 NM_152831
Function	Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Subcellular Location	Angiotensin-converting enzyme, soluble form: Secreted.
Tissue Specificity	Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. {ECO:0000269|PubMed:10924499, ECO:0000269|PubMed:10969042, ECO:0000269|PubMed:12459472, ECO:0000269|PubMed:15671045}.
Top Pathways	Hypertrophic cardiomyopathy (HCM), Chagas disease (American trypanosomiasis), Renin-angiotensin system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACE, testis-specific isoform precursor Gene - orb92721 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human ACE cDNA clone(NM_001178057.1) - CDFH000176 from Creative Biomart Species Human Accession NM_001178057.1

Human ACE ORF Clone(NM_152830.2) - CDCR320021 from Creative Biomart Species Human Accession NM_152830.2

Human ACE ORF Clone(NM_152830.2) - CDCR320200 from Creative Biomart Species Human Accession NM_152830.2

Human ACE ORF Clone(NM_000789.3) - CDCR337681 from Creative Biomart Species Human Accession NM_000789.3

Human ACE ORF Clone(NM_000789.3) - CDCR337682 from Creative Biomart Species Human Accession NM_000789.3

Human ACE ORF Clone(NM_001178057.1) - CDCR357248 from Creative Biomart Species Human Accession NM_001178057.1

Human ACE ORF Clone(NM_001178057.1) - CDCR357249 from Creative Biomart Species Human Accession NM_001178057.1

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone in cloning vector - HG11598-M from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11598-CH from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11598-CY from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11598-NF from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11598-ACR from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11598-CF from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11598-NM from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11598-CM from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11598-ACG from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11598-NY from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid - HG11598-UT from Sino Biological Species Human

Human Angiotensin Converting Enzyme 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11598-NH from Sino Biological Species Human

ACE - CL01040H02 from Elabscience Species Human Accession NM_001178057.1

ACE - CL01040H03 from Elabscience Species Human Accession NM_152830.2

Human ACE ORF Clone(NM_152830.2) - CDCR320021 from Creative biogene Species Human

Human ACE ORF Clone(NM_000789.3) - CDCR337681 from Creative biogene Species Human

Human ACE ORF clone (NM_001178057.1) - CDCR023698 from Creative biogene Species Human

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