Gene Symbol | GPT |
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Entrez Gene | 2875 |
Alt Symbol | AAT1, ALT1, GPT1 |
Species | Human |
Gene Type | protein-coding |
Description | glutamic-pyruvate transaminase (alanine aminotransferase) |
Other Description | GPT 1|alanine aminotransferase 1|glutamate pyruvate transaminase 1|glutamic--alanine transaminase 1|glutamic--pyruvic transaminase 1|glutamic-alanine transaminase 1 |
Swissprots | D3DWM7 P78398 B0YJ18 Q93076 P24298 |
Accessions | AAC51155 ACA05996 CBF80470 CBU99504 EAW82077 EAW82078 EAW82079 P24298 AI283141 AK225562 AK298488 BAG60697 AK303779 BAG64738 BC018207 AAH18207 BP275218 BT006992 AAP35638 D10355 BAA01186 DQ890596 ABM92213 DQ893764 ABM84690 XM_011516993 XP_011515295 NM_005309 NP_005300 |
Function | Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue. {ECO:0000269|PubMed:11863375}. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Carbon metabolism |
Active human Alanine Transaminase full length protein - ab77866 from Abcam
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Active human Alanine Transaminase full length protein - ab80419 from Abcam
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Human Alanine Transaminase full length protein - ab113862 from Abcam
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Human Alanine Transaminase full length protein - ab166920 from Abcam
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Human Alanine Transaminase peptide - ab90531 from Abcam
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GPT-Antibody-N-term-R133-Blocking-Peptide - BP7468b from Abgent, a WuXi AppTec company
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GPT-Antibody-N-term-P101-Blocking-Peptide - BP7468a from Abgent, a WuXi AppTec company
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GPT Protein Lysate (APL10454) - APL10454 from Aviva Systems Biology
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GPT Protein Lysate (APL10455) - APL10455 from Aviva Systems Biology
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GPT Protein Lysate (APL10456) - APL10456 from Aviva Systems Biology
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Glut. Pyruvate Transaminase Protein (OPMA04210) - OPMA04210 from Aviva Systems Biology
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Human GPT protein - orb245855 from Biorbyt
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Human GPT protein - orb244244 from Biorbyt
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Human ALT Protein - abx065206 from Abbexa
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Human ALT Protein - abx065202 from Abbexa
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Human ALT Protein - abx065207 from Abbexa
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Alanine aminotransferase 1 / ALT1 - BA290 from Acris Antibodies
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Alanine aminotransferase 1 / ALT1 - BA290X from Acris Antibodies
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Alanine aminotransferase 1 (ALT1) - H00002875-P01-10 from Acris Antibodies
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Alanine aminotransferase 1 (ALT1) - H00002875-P01-25 from Acris Antibodies
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Glutamic-Pyruvate Transaminase, Human Recombinant, Active - 228-10043-1 from RayBiotech
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Recombinant Human ALT1 / GPT - 228-10043-2 from RayBiotech
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Recombinant Human ALT1 / GPT - 228-10043-3 from RayBiotech
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Alanine Aminotransferase (ALT), Human - 20-6418 from ARP American Research Products
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Alanine Aminotransferase (ALT), Human - 20-6419 from ARP American Research Products
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