PVRL2

Gene Symbol PVRL2
Entrez Gene 5819
Alt Symbol CD112, HVEB, PRR2, PVRR2
Species Human
Gene Type protein-coding
Description poliovirus receptor-related 2 (herpesvirus entry mediator B)
Other Description herpesvirus entry protein B|nectin-2|poliovirus receptor-like 2
Swissprots A8K5L5 O75455 Q6IBI6 Q92692 Q96J29
Accessions AAC82347 AAC82348 AAD02503 AAQ19176 AAQ19177 AAQ19178 EAW57298 EAW57299 Q92692 AF058448 AAC23797 AJ708439 AK291330 BAF84019 BC003091 AAH03091 BQ549399 CN359643 CN410857 CR456818 CAG33099 DA198252 DQ891829 ABM82755 DQ895015 ABM85941 X80038 CAA56342 XM_011527192 XP_011525494 NM_001042724 NP_001036189 NM_002856 NP_002847
Function Probable cell adhesion protein. {ECO:0000269|PubMed:9657005}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Ubiquitous.
Top Pathways Adherens junction, Cell adhesion molecules (CAMs), Herpes simplex infection

Nectin 2 (D-11) - sc-373715 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 2 (D-11): sc-373715. Western blot analysis of human full length recombinant Nectin 2 fusion protein.

Nectin 2 (E-1) - sc-271236 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 2 (E-1) : sc-271236. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing membrane and cytoplasmic staining in  cells in seminiferous ducts and cytoplasmic staining in Leydig cells.

Nectin 2 (H-108) - sc-28638 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nectin 2 (H-108): sc-28638. Western blot analysis of human recombinant Nectin 2.

Nectin 2 (N-20) - sc-14799 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nectin 2 (N-20): sc-14799. Western blot analysis of human recombinant Nectin 2.

Nectin 2 (C-15) - sc-14802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Nectin 2 (R2.525) - sc-32804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 2 (R2.525): sc-32804. Western blot analysis of human recombinant Nectin 2 (A) and Nectin 2 expression in ECV304 whole cell lysate (B).

Nectin 2 (502-57) - sc-52708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rat
Clonality Monoclonal
Nectin 2 (502-57): sc-52708. Western blot analysis of Nectin 2 expression in non-transfected: sc-117752 (A) and mouse Nectin 2 transfected: sc-127214 (B) 293T whole cell lysates.

Nectin 2 (6A606) - sc-71660 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rat
Clonality Monoclonal
Nectin 2 (6A606): sc-71660. Western blot analysis of Nectin 2 expression in non-transfected: sc-117752 (A) and mouse Nectin 2 transfected: sc-127214 (B) 293T whole cell lysates.

Nectin 2 (B-C12) - sc-65333 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 2 (B-C12): sc-65333. Indirect FCM analysis of Jurkat cells stained with Nectin 2 (B-C12), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>2b</sub>: sc-3879.

Anti-Nectin 2 antibody - ab87220 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Nectin 2 antibody (ab87220) at 1 µg/ml + Brain (Human) Tissue Lysate - adult normal tissue (ab29466) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Nectin 2 antibody - ab88389 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Nectin 2 antibody (ab88389) at 1 µg/ml + Human spleen tissue lysate at 50 µg

Anti-Nectin 2 antibody - ab96158 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Nectin 2 antibody (ab96158) at 1/500 dilution + 293T whole cell lysate at 30 µg

Anti-Nectin 2 antibody [502-57] - ab16912 from Abcam

Prices $378.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 502-57

Anti-Nectin 2 antibody [B-C12] - ab47171 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-C12
A typical staining pattern with ab47171 monoclonal antibody of KG-1 cell line

Anti-Nectin 2 antibody [B-C12] - ab27344 from Abcam

Prices $378.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-C12
ICC/IF image of ab27344 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab27344, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Nectin 2 antibody [EPR6717] - ab135246 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6717
Overlay histogram showing HepG2 cells stained with ab135246 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab135246, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HepG2 cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-Nectin 2 antibody [R2.525] - ab23601 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone R2.525

Anti-Nectin 2 antibody - N-terminal - ab154895 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Nectin 2 antibody - N-terminal (ab154895) at 1/1000 dilution + MCF7 whole cell lysate at 30 µg

Anti-PVRL2 / CD112 Antibody (clone R2.525) - LS-C14124 from LifeSpan Bioscience

Prices $590.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone R2.525

Anti-PVRL2 / CD112 Antibody (Extracellular Domain, clone 502-57) - LS-C37481 from LifeSpan Bioscience

Prices $770.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 502-57

Anti-PVRL2 / CD112 Antibody (clone R2-525) - LS-C123154 from LifeSpan Bioscience

Prices $860.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone R2-525

Anti-PVRL2 / CD112 Antibody (clone TX31, FITC) - LS-C179435 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TX31

Anti-PVRL2 / CD112 Antibody (Extracellular Domain, clone 13A61, FITC) - LS-C183000 from LifeSpan Bioscience

Prices $770.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 13A61

Anti-PVRL2 / CD112 Antibody (aa32-360, clone TS106) - LS-C191469 from LifeSpan Bioscience

Prices $530.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone TS106

Anti-PVRL2 / CD112 Antibody (clone R2-525) - LS-C202322 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone R2-525
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