IL10

Gene Symbol IL10
Entrez Gene 3586
Alt Symbol CSIF, GVHDS, IL-10, IL10A, TGIF
Species Human
Gene Type protein-coding
Description interleukin 10
Other Description T-cell growth inhibitory factor|cytokine synthesis inhibitory factor|interleukin-10
Swissprots P22301
Accessions AAA80104 AAK19173 AAL06594 ABB01008 ACV30066 CAA51942 CAA55201 CAA82914 EAW93524 P22301 AF043333 AAC03534 AY029171 AAK38162 BC022315 BC104252 AAI04253 BC104253 AAI04254 CR541993 CAG46790 CR542028 CAG46825 EU751618 ACE95684 EU751619 ACE95685 M57627 AAA63207 XM_011509506 XP_011507808 NM_000572 NP_000563
Function Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Subcellular Location Secreted.
Tissue Specificity Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
Top Pathways Inflammatory bowel disease (IBD), Tuberculosis, Pertussis, African trypanosomiasis, Epstein-Barr virus infection

IL-10 (D13A11) XP ® Rabbit mAb (PE Conjugate) - 13360 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D13A11
Flow cytometric analysis of human peripheral blood mononuclear cells, untreated (left) or treated (right) with TPA #4174 (40 nM, 5 hr), Ionomycin, Calcium Salt #9995 (2 μM, 5 hr) and Brefeldin A #9972 (3 μg/ml, last 4 hr of stimulation), using a CD3-APC antibody and IL-10 (D13A11) XP ® Rabbit mAb (PE Conjugate). Analysis was performed on cells in the lymphocyte gate.

IL-10 (D13A11) XP ® Rabbit mAb - 12163 from Cell Signaling Technology

Prices $277.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D13A11
Western blot analysis of extracts from purified CD4 + human peripheral blood mononuclear cells, activated with anti-CD3 and anti-CD28 in regulatory T cell inducing conditions for 12 d and then untreated (-) or treated (+) with TPA #4174 (40 nM, 6 hr), Ionomycin #9995 (3 μM, 6 hr), and Brefeldin A #9972 (300 ng/mL, last 5 hr of stimulation), using IL-10 (D13A11) XP ® Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

IL-10 (3C12C12) - sc-32815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-10 (3C12C12): sc-32815. Western blot analysis of human recombinant IL-10.

IL-10 (E-10) - sc-8438 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-10 (E-10): sc-8438. Western blot analysis of human recombinant IL-10.

IL-10 (H-160) - sc-7888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-10 (H-160): sc-7888. Western blot analysis of human recombinant IL-10.

IL-10 (JES3-19F1) - sc-53705 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rat
Clonality Monoclonal

IL-10 (A00045.01) - sc-81028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-10 (23738.11) - sc-57244 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-IL10 antibody - ab34843 from Abcam

Prices $394.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
ab34843 staining IL10 in Human colon tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with paraformaldehyde and blocked with 1% BSA for 20 minutes at 25°C; antigen retrieval was by heat mediation. Samples were incubated with primary antibody (1/200 in 1% BSA in PBS) for 16 hours at 4°C. An undiluted HRP-conjugated goat anti-rabbit polyclonal IgG was used as the secondary antibody. See Abreview

Anti-IL10 antibody - ab134742 from Abcam

Prices $376.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Immunohistochemical analysis of paraffin embedded Human pancreas adenocarcinoma tissue labelling IL10 with ab134742 antibody at a concentration of 5 µg/ml.

Anti-IL10 antibody - ab10775 from Abcam

Prices $372.00
Sizes 200 µg
Host Goat
Clonality Polyclonal

Anti-IL10 antibody - ab95062 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab95062 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab95062 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-IL10 antibody - ab9611 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL10 antibody - ab187251 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IL10 antibody (ab187251) at 1/1000 dilution + Human IL10 recombinant protein at 10 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-IL10 antibody - ab157756 from Abcam

Host Sheep
Clonality Polyclonal

Anti-IL10 antibody [23738.11] - ab10774 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 23738.11

Anti-IL10 antibody [945A5A10] (Biotin) - ab16233 from Abcam

Prices $372.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 945A5A10

Anti-IL10 antibody [B-S10] - ab22771 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-S10

Anti-IL10 antibody [B-S10] - ab47222 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-S10
We examined the effect of anti IL-10 to study the regulatory role of IL-10 and the interaction of IL-10 with its receptor. Measurement of neutralizing activity of anti IL-10 by TNFa-ELISA. IL-10 decreased the LPS-induced production of TNFa by Monocytes and recombinant IL-10 is neutralized by increasing concentrations of anti IL-10 antibody. The TNFa production showed a dependence on antibody concentration of anti IL-10.ab47222 used at a 1/2000 dilution.See Abreview

Anti-IL10 antibody (Biotin) - ab84031 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-IL10 antibody [EP1115Y] - ab52909 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1115Y
Anti-IL10 antibody [EP1115Y] (ab52909) at 1/5000 dilution + Recombinant protein (5ng)SecondaryGoat anti-Rabbit HRP labeled at 1/2000 dilution

Anti-IL10 antibody [EPR1114] - ab133575 from Abcam

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1114
All lanes : Anti-IL10 antibody [EPR1114] (ab133575) at 1/1000 dilutionLane 1 : LPS-treated THP1 cell lysateLane 2 : THP1 cell lysateLane 3 : Ramos cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-IL-10 Antibody - LS-C8068 from LifeSpan Bioscience

Prices $515.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-IL10 Antibody - LS-C8069 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL-10 Antibody - LS-C8074 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
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