| Gene Symbol |
IL10
|
| Entrez Gene |
3586
|
| Alt Symbol |
CSIF, GVHDS, IL-10, IL10A, TGIF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 10
|
| Other Description |
T-cell growth inhibitory factor|cytokine synthesis inhibitory factor|interleukin-10
|
| Swissprots |
P22301
|
| Accessions |
AAA80104 AAK19173 AAL06594 ABB01008 ACV30066 CAA51942 CAA55201 CAA82914 EAW93524 P22301 AF043333 AAC03534 AY029171 AAK38162 BC022315 BC104252 AAI04253 BC104253 AAI04254 CR541993 CAG46790 CR542028 CAG46825 EU751618 ACE95684 EU751619 ACE95685 M57627 AAA63207 XM_011509506 XP_011507808 NM_000572 NP_000563
|
| Function |
Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
|
| Top Pathways |
Inflammatory bowel disease (IBD), Tuberculosis, Pertussis, African trypanosomiasis, Epstein-Barr virus infection
|
