Gene Symbol | IL10 |
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Entrez Gene | 3586 |
Alt Symbol | CSIF, GVHDS, IL-10, IL10A, TGIF |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 10 |
Other Description | T-cell growth inhibitory factor|cytokine synthesis inhibitory factor|interleukin-10 |
Swissprots | P22301 |
Accessions | AAA80104 AAK19173 AAL06594 ABB01008 ACV30066 CAA51942 CAA55201 CAA82914 EAW93524 P22301 AF043333 AAC03534 AY029171 AAK38162 BC022315 BC104252 AAI04253 BC104253 AAI04254 CR541993 CAG46790 CR542028 CAG46825 EU751618 ACE95684 EU751619 ACE95685 M57627 AAA63207 XM_011509506 XP_011507808 NM_000572 NP_000563 |
Function | Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. |
Subcellular Location | Secreted. |
Tissue Specificity | Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. |
Top Pathways | Inflammatory bowel disease (IBD), Tuberculosis, Pertussis, African trypanosomiasis, Epstein-Barr virus infection |
IL-10 CRISPR/Cas9 KO Plasmid (h) - sc-417060 from Santa Cruz Biotechnology
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IL-10 HDR Plasmid (h) - sc-417060-HDR from Santa Cruz Biotechnology
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IL-10 Double Nickase Plasmid (h) - sc-417060-NIC from Santa Cruz Biotechnology
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IL-10 Double Nickase Plasmid (h2) - sc-417060-NIC-2 from Santa Cruz Biotechnology
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IL-10 CRISPR Activation Plasmid (h) - sc-417060-ACT from Santa Cruz Biotechnology
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IL-10 CRISPR Activation Plasmid (h2) - sc-417060-ACT-2 from Santa Cruz Biotechnology
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IL-10 Lentiviral Activation Particles (h) - sc-417060-LAC from Santa Cruz Biotechnology
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IL-10 Lentiviral Activation Particles (h2) - sc-417060-LAC-2 from Santa Cruz Biotechnology
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IL-10 siRNA (h) - sc-39634 from Santa Cruz Biotechnology
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IL-10 shRNA Plasmid (h) - sc-39634-SH from Santa Cruz Biotechnology
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IL-10 shRNA (h) Lentiviral Particles - sc-39634-V from Santa Cruz Biotechnology
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IL-10 RNAi - H00003586-R01 from Novus Biologicals
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MISSION® esiRNA - EHU145171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1749 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1749 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08067 from Sigma-Aldrich
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IL10 siRNA (Human) - CRH2396 from Cohesion Biosciences
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IL10 - MBS8217845 from MyBioSource
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shRNA set against Human IL10(NM_000572.2) - SHL170570 from Creative biogene
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IL10 shRNA Plasmid (Human) - CHH2396 from Cohesion Biosciences
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IL10 miRNA 3'UTR clone - MiUTR1H-04870 from Creative biogene
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