Gene Symbol |
CKMT2
|
Entrez Gene |
1160
|
Alt Symbol |
SMTCK
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
creatine kinase, mitochondrial 2 (sarcomeric)
|
Other Description |
S-MtCK|basic-type mitochondrial creatine kinase|creatine kinase S-type, mitochondrial|mib-CK|sarcomeric mitochondrial creatine kinase
|
Swissprots |
Q8N1E1 Q6ICS8 P17540
|
Accessions |
EAW95865 EAW95866 EAW95867 P17540 AK122769 BAG53719 AK313293 BAG36100 AW300490 BC029140 AAH29140 CR450315 CAG29311 DA826840 DB479765 DC308656 DQ890781 ABM81707 EU176501 ABW03302 J05401 AAA60561 NM_001099735 NP_001093205 NM_001099736 NP_001093206 NM_001825 NP_001816
|
Function |
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
|
Subcellular Location |
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
|
Tissue Specificity |
Sarcomere-specific. Found only in heart and skeletal muscles.
|
Top Pathways |
Arginine and proline metabolism
|