Gene Symbol | CKMT2 |
---|---|
Entrez Gene | 1160 |
Alt Symbol | SMTCK |
Species | Human |
Gene Type | protein-coding |
Description | creatine kinase, mitochondrial 2 (sarcomeric) |
Other Description | S-MtCK|basic-type mitochondrial creatine kinase|creatine kinase S-type, mitochondrial|mib-CK|sarcomeric mitochondrial creatine kinase |
Swissprots | Q8N1E1 Q6ICS8 P17540 |
Accessions | EAW95865 EAW95866 EAW95867 P17540 AK122769 BAG53719 AK313293 BAG36100 AW300490 BC029140 AAH29140 CR450315 CAG29311 DA826840 DB479765 DC308656 DQ890781 ABM81707 EU176501 ABW03302 J05401 AAA60561 NM_001099735 NP_001093205 NM_001099736 NP_001093206 NM_001825 NP_001816 |
Function | Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. |
Tissue Specificity | Sarcomere-specific. Found only in heart and skeletal muscles. |
Top Pathways | Arginine and proline metabolism |