Gene Symbol | CKMT2 |
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Entrez Gene | 1160 |
Alt Symbol | SMTCK |
Species | Human |
Gene Type | protein-coding |
Description | creatine kinase, mitochondrial 2 (sarcomeric) |
Other Description | S-MtCK|basic-type mitochondrial creatine kinase|creatine kinase S-type, mitochondrial|mib-CK|sarcomeric mitochondrial creatine kinase |
Swissprots | Q8N1E1 Q6ICS8 P17540 |
Accessions | EAW95865 EAW95866 EAW95867 P17540 AK122769 BAG53719 AK313293 BAG36100 AW300490 BC029140 AAH29140 CR450315 CAG29311 DA826840 DB479765 DC308656 DQ890781 ABM81707 EU176501 ABW03302 J05401 AAA60561 NM_001099735 NP_001093205 NM_001099736 NP_001093206 NM_001825 NP_001816 |
Function | Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. |
Tissue Specificity | Sarcomere-specific. Found only in heart and skeletal muscles. |
Top Pathways | Arginine and proline metabolism |
sMtCK CRISPR/Cas9 KO Plasmid (h) - sc-408716 from Santa Cruz Biotechnology
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sMtCK HDR Plasmid (h) - sc-408716-HDR from Santa Cruz Biotechnology
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sMtCK Double Nickase Plasmid (h) - sc-408716-NIC from Santa Cruz Biotechnology
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sMtCK Double Nickase Plasmid (h2) - sc-408716-NIC-2 from Santa Cruz Biotechnology
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sMtCK CRISPR Activation Plasmid (h) - sc-408716-ACT from Santa Cruz Biotechnology
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sMtCK CRISPR Activation Plasmid (h2) - sc-408716-ACT-2 from Santa Cruz Biotechnology
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sMtCK Lentiviral Activation Particles (h) - sc-408716-LAC from Santa Cruz Biotechnology
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sMtCK Lentiviral Activation Particles (h2) - sc-408716-LAC-2 from Santa Cruz Biotechnology
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sMtCK siRNA (h) - sc-38969 from Santa Cruz Biotechnology
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sMtCK shRNA Plasmid (h) - sc-38969-SH from Santa Cruz Biotechnology
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sMtCK shRNA (h) Lentiviral Particles - sc-38969-V from Santa Cruz Biotechnology
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MISSION® siRNA - SIHK0438 from Sigma-Aldrich
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MISSION® siRNA - SIHK0439 from Sigma-Aldrich
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MISSION® siRNA - SIHK0437 from Sigma-Aldrich
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MISSION® siRNA - SIHK0442 from Sigma-Aldrich
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MISSION® siRNA - SIHK0440 from Sigma-Aldrich
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MISSION® siRNA - SIHK0441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6157 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6157 from Sigma-Aldrich
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CKMT2 siRNA (Human) - CRH0832 from Cohesion Biosciences
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CKMT2 RNAi - H00001160-R02 from Novus Biologicals
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CKMT2 - MBS8200494 from MyBioSource
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shRNA set against Human CKMT2 (NM_001825.2) - SHH264413 from Creative biogene
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shRNA set against Human CKMT2(NM_001825.2) - SHG179737 from Creative biogene
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CKMT2 shRNA Plasmid (Human) - CHH0832 from Cohesion Biosciences
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