CCNL1

Gene Symbol CCNL1
Entrez Gene 57018
Alt Symbol ANIA6A, BM-001, PRO1073, ania-6a
Species Human
Gene Type protein-coding
Description cyclin L1
Other Description cyclin L ania-6a|cyclin L gamma|cyclin-L|cyclin-L1
Swissprots Q9NZF3 Q96QT0 Q6UWS7 Q8NI48 B3KMY3 Q9UK58 Q6NVY9
Accessions CBX53839 EAW78712 EAW78713 EAW78714 Q9UK58 AF180920 AAD53184 AF208843 AAF64257 AF367476 AAM21204 AF367477 AAM21205 AK022974 BAG51145 AK098021 AK122738 AK125606 AY034790 AAK61551 AY358663 AAQ89026 BC007081 AAH07081 BC038394 AAH38394 BC067812 AAH67812 BQ024284 BQ027163 BX641146 BX647554 JF432881 ADZ16098 XM_005247647 XP_005247704 XM_005247648 XP_005247705 XM_005247649 XP_005247706 XM_005247650 XP_005247707 XM_005247651 XP_005247708 XM_006713710 XP_006713773 XM_011513011 XP_011511313 NM_001308185 NP_001295114 NM_020307 NP_064703
Function Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21. {ECO:0000269|PubMed:11980906, ECO:0000269|PubMed:12414649, ECO:0000269|PubMed:15700036}.
Subcellular Location Nucleus speckle {ECO:0000250}. Note=More specifically found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing. {ECO:0000250}.
Tissue Specificity Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC). {ECO:0000269|PubMed:11980906, ECO:0000269|PubMed:12414649, ECO:0000269|PubMed:15700036}.

Human CCNL1 full length protein - ab163463 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab163463 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CCNL1 peptide - orb218593 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Drosophila

Cyclin L1 Blocking Peptide - abx063924 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Dog, Pig

Cyclin L1 - H00057018-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Cyclin L1 - H00057018-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CCNL1 fusion protein - ag3731 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Cyclin L1 Blocking Peptide - CBP2730 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Dog, Pig

Cyclin L1 (E491) Peptide - BS1285P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Human Cyclin-L1(CCNL1) - CSB-YP892449HU CSB-EP892449HU CSB-BP892449HU CSB-MP892449HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CCNL1-Antibody-C-term-Blocking-Peptide - BP6610b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Cyclin-L1 (CCNL1), Recombinant Protein - MBS1313053 from MyBioSource

Category Protein
Prices $915.00, $915.00, $1,140.00, $1,140.00, $1,360.00, $1,360.00, $1,815.00, $1,815.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Orangutan

Cyclin-L1 (CCNL1), Recombinant Protein - MBS1301303 from MyBioSource

Category Protein
Prices $1,315.00, $1,315.00, $1,535.00, $1,535.00, $2,170.00, $2,170.00, $2,635.00, $2,635.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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