Gene Symbol | SLC7A2 |
---|---|
Entrez Gene | 6542 |
Alt Symbol | ATRC2, CAT2, HCAT2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
Other Description | cationic amino acid transporter 2|low affinity cationic amino acid transporter 2 |
Swissprots | B7ZL54 P52569 Q6NSZ7 O15292 Q86TC6 Q14CQ6 O15291 |
Accessions | EAW63812 EAW63813 EAW63814 EAW63815 P52569 AA724796 AI275549 AI458117 AK314287 AL512749 AL832016 CAD89909 AU077312 BC069648 AAH69648 BC104905 AAI04906 BC113661 AAI13662 BC143583 AAI43584 CB216457 D29990 BAA06271 D78212 DB237902 U76368 AAB62810 U76369 AAB62811 XM_005273610 XP_005273667 XM_005273611 XP_005273668 XM_005273612 XP_005273669 NM_001008539 NP_001008539 NM_001164771 NP_001158243 NM_003046 NP_003037 |
Function | Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport. {ECO:0000250|UniProtKB:P18581, ECO:0000269|PubMed:9174363}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:9174363}; Multi-pass membrane protein {ECO:0000269|PubMed:9174363}. |
Tissue Specificity | Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart. {ECO:0000269|PubMed:8954799}. |
Human SLC7A2 full length protein - ab159526 from Abcam
|
||||||||||
Human SLC7A2 protein fragment - ab159527 from Abcam
|
||||||||||
SLC7A2 Antibody Blocking Peptide - LS-E16091 from LifeSpan Bioscience
|
||||||||||
SLC7A2 Antibody Blocking Peptide - LS-E29603 from LifeSpan Bioscience
|
||||||||||
SLC7A2 Antibody Blocking Peptide - LS-E29604 from LifeSpan Bioscience
|
||||||||||
Recombinant Human SLC7A2 Protein - H00006542-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human SLC7A2 Protein - H00006542-P01 from Novus Biologicals
|
||||||||||
SLC7A2-Antibody-C-term-Blocking-peptide - BP11660b from Abgent, a WuXi AppTec company
|
||||||||||
SLC7A2 Blocking Peptide - 33R-9430 from Fitzgerald
|
||||||||||
SLC7A2 / CAT2 - H00006542-P01 from Acris Antibodies
|
||||||||||
SLC7A2 / CAT2 - H00006542-Q01-10 from Acris Antibodies
|
||||||||||
SLC7A2 / CAT2 - H00006542-Q01-25 from Acris Antibodies
|
||||||||||
SLC7A2 fusion protein - ag17684 from Proteintech Group
|
||||||||||
SLC7A2 fusion protein - ag17682 from Proteintech Group
|
||||||||||
Recombinant Cationic Amino Acid Transporter 2 (CAT2) - RPE402Ra01 from Uscn Life Science Inc.
|
||||||||||
SLC7A2 / CAT2 (transcript variant 2) - TP310214 from Acris Antibodies
|
||||||||||
SLC7A2 Peptide, Human - M34GP14644H from Creative Peptides
|
||||||||||
Low affinity cationic amino acid transporter 2 (SLC7A2), Recombinant Protein - MBS950149 from MyBioSource
|
||||||||||