| Gene Symbol |
CINP
|
| Entrez Gene |
51550
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cyclin-dependent kinase 2 interacting protein
|
| Other Description |
CDK2-interacting protein|cyclin-dependent kinase 2-interacting protein
|
| Swissprots |
Q9NPF9 F5H8A7 F5H7P3 Q9BW66
|
| Accessions |
EAW81785 EAW81786 Q9BW66 AF228148 AAF44747 AF228149 AAF44748 AK056112 BAB71095 BC000600 AAH00600 BU174070 BX248279 CAD62607 CR457178 CAG33459 DA167716 DA351468 DA699021 EL951117 XM_005267753 XP_005267810 XM_011536830 XP_011535132 XM_011536831 XP_011535133 NM_032630 NP_116019 NM_001177611 NM_001177612
|
| Function |
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling. {ECO:0000269|PubMed:16082200, ECO:0000269|PubMed:19889979}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:19889979}. Note=Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
|