Gene Symbol | CINP |
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Entrez Gene | 51550 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cyclin-dependent kinase 2 interacting protein |
Other Description | CDK2-interacting protein|cyclin-dependent kinase 2-interacting protein |
Swissprots | Q9NPF9 F5H8A7 F5H7P3 Q9BW66 |
Accessions | EAW81785 EAW81786 Q9BW66 AF228148 AAF44747 AF228149 AAF44748 AK056112 BAB71095 BC000600 AAH00600 BU174070 BX248279 CAD62607 CR457178 CAG33459 DA167716 DA351468 DA699021 EL951117 XM_005267753 XP_005267810 XM_011536830 XP_011535132 XM_011536831 XP_011535133 NM_032630 NP_116019 NM_001177611 NM_001177612 |
Function | Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling. {ECO:0000269|PubMed:16082200, ECO:0000269|PubMed:19889979}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19889979}. Note=Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication. |
Human CINP full length protein - ab38229 from Abcam
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Human CINP full length protein - ab109973 from Abcam
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CINP Recombinant Protein - H00051550-P01 from Novus Biologicals
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CINP Partial Recombinant Protein - H00051550-Q01 from Novus Biologicals
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Recombinant Human CINP Protein - NBP1-72364 from Novus Biologicals
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Human CINP protein - orb168120 from Biorbyt
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CINP protein (His tag) - 80R-1876 from Fitzgerald
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CINP (1-212, His-tag) - AR39058PU-L from Acris Antibodies
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CINP (1-212, His-tag) - AR39058PU-N from Acris Antibodies
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CINP - H00051550-P01-02 from Acris Antibodies
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CINP - H00051550-Q01-10 from Acris Antibodies
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CINP - H00051550-Q01-25 from Acris Antibodies
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CINP, 1-212aa, Human, His tag, E.coli - 01-P1118 from ARP American Research Products
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CINP fusion protein - Ag7089 from Proteintech Group
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CINP fusion protein - Ag7033 from Proteintech Group
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CINP Human - PKPS-276 from NeoScientific
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Recombinant Human Cyclin-Dependent Kinase 2 Interacting Protein - BP002745-PKA-269 from Syd Labs
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CINP, 1-212aa, Recombinant Protein - GWB-P0920J from Genway Biotech
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Recombinant Human CINP, His-tagged - CINP-3563H from Creative Biomart
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Recombinant Human Cyclin-Dependent Kinase 2 InteractingProtein, T7-tagged - CINP-2915H from Creative Biomart
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Recombinant Human CINP, His-tagged - CINP-27247TH from Creative Biomart
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Recombinant Human CINP - CINP-27249TH from Creative Biomart
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Recombinant Human CINP, His-tagged - CINP-11250H from Creative Biomart
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CINP 1-212aa - CMB-951 from Reagent Proteins
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Recombinant human Cyclin-dependent kinase 2-interacting protein - CSB-EP861151HU CSB-BP861151HU CSB-MP861151HU from Cusabio
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