CTR9

Gene Symbol CTR9
Entrez Gene 9646
Alt Symbol SH2BP1, TSBP, p150, p150TSP
Species Human
Gene Type protein-coding
Description CTR9, Paf1/RNA polymerase II complex component
Other Description Ctr9, Paf1/RNA polymerase II complex component, homolog|RNA polymerase-associated protein CTR9 homolog|SH2 domain binding protein 1 (tetratricopeptide repeat containing)|SH2 domain-binding protein 1|TPR-containing, SH2-binding phosphoprotein
Swissprots D3DQV8 Q15015 Q6PD62
Accessions CCQ43449 EAW68557 EAW68558 Q6PD62 AK291794 BAF84483 BC014335 BC058914 AAH58914 BP223102 BP250198 D63875 BAA09925 NM_014633 NP_055448
Function Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non- phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex
Subcellular Location Nucleus speckle {ECO:0000250}. Note=Found in speckles. {ECO:0000250}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:8590280}.

CTR9 (D1Z4F) Rabbit mAb - 12619 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1Z4F
Western blot analysis of extracts from various cell lines using CTR9 (D1Z4F) Rabbit mAb.

CTR9 (E-16) - sc-68460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CTR9 (E-16): sc-68460. Western blot analysis of CTR9 expression in HeLa (A), Raji (B) and NIH/3T3 (C) whole cell lysates.

CTR9 (N-18) - sc-68462 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CTR9 antibody - ab84487 from Abcam

Prices $380.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84487 at 1/250 dilution staining formalin-fixed, paraffin-embedded section of human breast carcinoma by immunohistochemistry. Detection: DAB staining.

Anti-CTR9 antibody - ab101459 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CTR9 antibody (ab101459) at 1/1000 dilution + A431 whole cell ysate at 30 µg

Anti-CTR9 antibody - ab130983 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CTR9 antibody (ab130983) at 1 µg/ml + Jurkat cell lysate at 10 µgSecondaryGoat anti-Rabbit IgG HRP

Anti-CTR9 antibody - C-terminal - ab202309 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CTR9 antibody - C-terminal (ab202309) at 1/1000 dilutionLane 1 : A431 cell lysateLane 2 : HT29 cell lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L(HRP) at 1/10000 dilutiondeveloped using the ECL technique

Anti-CTR9 Antibody - LS-C332704 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cell line, using CTR9 antibody.

Anti-CTR9 Antibody (aa1055-1104) - LS-C151791 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTR9 antibody Western Blot of Human 721_B. Antibody Dilution: 1.0 ug/ml. CTR9 is supported by BioGPS gene expression data to be expressed in 721_B. Antibody dilution: 1 ug/ml.

Anti-CTR9 Antibody (aa1022-1056) - LS-C344436 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of lysates from A431, HT-29 cell line (from left to right) with Mouse Ctr9 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-CTR9 Antibody (aa1123-1173) - LS-C288189 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Human CTR9 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-CTR9 Antibody (aa1123-1173) - LS-C286527 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Mouse CTR9 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-CTR9 used at a dilution of 1:250.

CTR9 Antibody - NB100-68205 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTR9 Antibody - NBP2-16031 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CTR9 Antibody [NBP2-16031] - A. 30 ug 293T whole cell lysate/extract B. 30 ug A431 whole cell lysate/extract C. 30 ug HeLa whole cell lysate/extract D. 30 ug HepG2 whole cell lysate/extract 5 % SDS-PAGE CTR9 antibody dilution: 1:1000

CTR9 Polyclonal Antibody - bs-3697R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TSBP Polyclonal Antibody - bs-9531R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CTR9 (576-590) antibody produced in rabbit - SAB1100738 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-CTR9 (576-590) : <B>Cat. No. SAB1100738</B>: Immunofluorescence of HUVEC cells using CTR9 (576-590) , Cat. No. SAB1100738 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-CTR9 (N-terminal) antibody produced in rabbit - SAB2700513 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CTR9 (N-terminal): <B>Cat. No. SAB2700513</B>: Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using CTR9 antibody at 1:500 dilution.

CTR9 antibody - C-terminal region (ARP64690_P050) - ARP64690_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTR9 antibody - 70R-16656 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti -CTR9 (Paf1/RNA Polymerase II Complex Component, TSBP, p150, SH2BP1, p150TSP) - 210322 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

CTR9 Polyclonal Antibody - A3659 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cells, using CTR9 antibody.

CTR9 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-3697R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTR9 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-3697R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTR9 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-3697R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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