NSMCE4A

Gene Symbol NSMCE4A
Entrez Gene 54780
Alt Symbol C10orf86, NS4EA, NSE4A
Species Human
Gene Type protein-coding
Description non-SMC element 4 homolog A (S. cerevisiae)
Other Description non-structural maintenance of chromosomes element 4 homolog A
Swissprots Q6P673 Q9BS90 Q5SQQ5 Q8WY66 Q9NXX6
Accessions EAW49330 EAW49331 EAW49332 EAW49333 Q9NXX6 AF258584 AAG23787 AK000010 BAA90881 AK056579 AK222487 BAD96207 AK301658 BAG63134 AK308687 BC005212 AAH05212 BC062427 AAH62427 DA567626 XM_005269928 XP_005269985 XM_005269929 XP_005269986 XM_005269930 XP_005269987 XM_011539909 XP_011538211 XM_011539910 XP_011538212 XR_428706 NM_001167865 NP_001161337 NM_017615 NP_060085
Function Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus. {ECO:0000269|PubMed:18086888}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18086888}. Chromosome, telomere {ECO:0000305|PubMed:18086888}.

NSE4A CRISPR/Cas9 KO Plasmid (h) - sc-412333 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A HDR Plasmid (h) - sc-412333-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A Double Nickase Plasmid (h) - sc-412333-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A Double Nickase Plasmid (h2) - sc-412333-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A CRISPR Activation Plasmid (h) - sc-412333-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A CRISPR Activation Plasmid (h2) - sc-412333-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A Lentiviral Activation Particles (h) - sc-412333-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A Lentiviral Activation Particles (h2) - sc-412333-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSE4A siRNA (h) - sc-90496 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NSE4A shRNA Plasmid (h) - sc-90496-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NSE4A shRNA (h) Lentiviral Particles - sc-90496-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU087011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15537 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15537 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00398 from Sigma-Aldrich

Category miRNA

NSMCE4A siRNA (Human) - CRJ0213 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NSMCE4A (NM_017615.2) - SHH355416 from Creative biogene

Category siRNA
Species Reactivities Human

Human NSMCE4A siRNA - orb270714 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NSMCE4A shRNA Plasmid (Human) - CHJ0213 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NSMCE4A miRNA 3'UTR clone - MiUTR3H-12714 from Creative biogene

Species Reactivities Human
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