GULP1

Gene Symbol GULP1
Entrez Gene 51454
Alt Symbol CED-6, CED6, GULP
Species Human
Gene Type protein-coding
Description GULP, engulfment adaptor PTB domain containing 1
Other Description PTB domain adapter protein CED-6|PTB domain adaptor protein CED-6|PTB domain-containing engulfment adapter protein 1|cell death protein 6 homolog|engulfment adapter protein
Swissprots Q53PC1 B4DQ40 Q9UBP9 D3DPH1 B2RB51 Q53RF3 Q9BVL3 B8ZZ72 E9PB86
Accessions AAX93242 AAY24122 CAC07438 EAX10913 EAX10914 EAX10915 EAX10916 EAX10917 Q9UBP9 AB209890 BAD93127 AF075014 AF191771 AAF18975 AF200715 AAF08006 AK023668 BAG51214 AK055718 AK130507 AK298626 BAG60802 AK314498 BAG37098 AL080142 AW149992 BC001103 AAH01103 BC068525 CD627760 DA392794 XM_006712580 XP_006712643 XM_006712581 XP_006712644 XM_006712582 XP_006712645 XM_006712583 XP_006712646 XM_006712584 XP_006712647 XM_006712585 XP_006712648 XM_006712589 XP_006712652 XM_006712590 XP_006712653 XM_011511327 XP_011509629 XM_011511328 XP_011509630 XM_011511329 XP_011509631 XM_011511330 XP_011509632 XM_011511331 XP_011509633 XM_011511332 XP_011509634 XM_011511333 XP_011509635 XM_011511334 XP_011509636 XM_011511335 XP_011509637 NM_001252668 NP_001239597 NM_001252669 NP_001239598 NM_016315 NP_057399 NR_045562 NR_045563
Function May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. {ECO:0000269|PubMed:10574763, ECO:0000269|PubMed:10574771, ECO:0000269|PubMed:16497666, ECO:0000269|PubMed:17398097}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16497666}. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes.
Tissue Specificity Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. {ECO:0000269|PubMed:10574763}.

GULP (E-4) - sc-374591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GULP (E-4): sc-374591. Western blot analysis of GULP expression in Caki-1 whole cell lysate.

GULP (H-300) - sc-135070 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GULP (H-300): sc-135070. Western blot analysis of GULP expression in Caki-1 (A), Hep G2 (B), MOLT-4 (C), NIH/3T3 (D) and CCRF-CEM (E) whole cell lysates and human placenta tissue extract (F).

GULP (P-19) - sc-54528 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GULP (P-19): sc-54528. Western blot analysis of GULP expression in Caki-1 whole cell lysate.

GULP (S-18) - sc-54527 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CED6 antibody - ab85944 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab85944 at 5µg/ml staining CED6 in human kidney by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

Anti-CED6 antibody - ab97669 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CED6 antibody (ab97669) at 1/1000 dilutionLane 1 : HepG2 whole cell lysateLane 2 : MOLT4 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-CED6 antibody - ab103642 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CED6 antibody (ab103642) at 1/100 dilution + CEM cell lysate at 35 µg

Anti-CED6 antibody - ab2751 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab2751 at 5ug/ml staining CED6 in human kidney tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). The AP-staining procedure was used for detection.

Anti-CED6 antibody - ab133825 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CED6 antibody (ab133825) at 1 µg/ml + Human fetal brain lysate at 10 µg

Anti-CED6 / GULP1 Antibody (aa29-78) - LS-C151982 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CED6 / GULP1 antibody Western Blot of Fetal Brain.

Anti-CED6 / GULP1 Antibody - LS-C332565 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using GULP1 antibody.

Anti-CED6 / GULP1 Antibody (Internal) - LS-C345123 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of GULP1 Antibody with human HepG2 Whole Cell lysate.

Anti-CED6 / GULP1 Antibody (aa241-304) - LS-C185910 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: NIH-3T3. 10% SDS PAGE. GULP1 antibody. CED6 / GULP1 antibody diluted at 1:1000.

Anti-CED6 / GULP1 Antibody (C-Terminus) IHC-plus™ - LS-B2273 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-GULP1 / CED6 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2273 concentration 5 ug/ml.

GULP1/CED-6 Antibody - AF7978 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of K562 human chronic myelogenous leukemia cell line, MEF mouse embryonic feeder cells, and Rat‑2 rat embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human/Mouse/Rat GULP1/CED-6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7978) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for GULP1/CED-6 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

GULP1/CED-6 Antibody - NBP1-84553 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GULP1/CED-6 Antibody [NBP1-84553] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

GULP1/CED-6 Antibody - NB100-1042 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

GULP1/CED-6 Antibody - H00051454-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

CED6 Polyclonal Antibody - bs-13626R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CED6 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13626R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CED6 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13626R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CED6 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13626R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CED6 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13626R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CED6 Polyclonal Antibody, Cy3 Conjugated - bs-13626R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CED6 Polyclonal Antibody, Cy5 Conjugated - bs-13626R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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