Gene Symbol | AP5M1 |
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Entrez Gene | 55745 |
Alt Symbol | C14orf108, MUDENG, Mu5, MuD |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 5, mu 1 subunit |
Other Description | AP-5 complex subunit mu|AP-5 complex subunit mu-1|MHD domain-containing death-inducing protein|MU-2/AP1M2 domain containing, death-inducing|Mu-2 related death-inducing|adapter-related protein complex 5 mu subunit|adapter-related protein complex 5 subunit mu-1|adaptor-related protein complex 5 subunit mu-1|mu-2-related death-inducing protein|putative HIV-1 infection-related protein |
Swissprots | Q96DX3 Q6ZMD7 Q9H0R1 O95354 Q9NVC5 |
Accessions | EAW80700 EAW80701 EAW80702 EAW80703 Q9H0R1 AF094583 AAC78130 AK001675 BAA91828 AK024921 AK172824 BAD18791 AK225345 AK303999 BAG64916 AL136685 CAB66620 BC013174 AAH13174 BQ000414 CN352262 DB204683 XM_006720196 XP_006720259 XM_011536940 XP_011535242 NM_018229 NP_060699 NR_026895 |
Function | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death. {ECO:0000269|PubMed:18395520, ECO:0000269|PubMed:22022230}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:22022230}. Late endosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Lysosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Note=May cycle on and off membranes. |
Tissue Specificity | Expressed in various tumor cell lines including Jurkat, Hep-G2 and HeLa. {ECO:0000269|PubMed:18395520}. |
MUDENG (H-97) - sc-383028 from Santa Cruz Biotechnology
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MUDENG (N-16) - sc-165044 from Santa Cruz Biotechnology
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Anti-AP5M1 antibody - C-terminal - ab173959 from Abcam
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Anti-AP5M1 / C14orf108 Antibody (aa355-384, Biotin) - LS-C223390 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa355-384, APC) - LS-C223388 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa355-384, AP) - LS-C223387 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa355-384, Azide-free, HRP) - LS-C223392 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa355-384, FITC) - LS-C223391 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa355-384, PE) - LS-C223393 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa355-384) - LS-C329856 from LifeSpan Bioscience
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Anti-AP5M1 / C14orf108 Antibody (aa356-384) - LS-C158330 from LifeSpan Bioscience
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MUDENG Antibody - NBP2-33765 from Novus Biologicals
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MUDENG Antibody - NBP2-33815 from Novus Biologicals
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Anti-AP5M1 antibody produced in rabbit - HPA057098 from Sigma-Aldrich
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ANTI-MUDEN (C-TERM) antibody produced in rabbit - SAB1302404 from Sigma-Aldrich
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Anti-AP5M1 antibody produced in rabbit - HPA055768 from Sigma-Aldrich
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MUDEN-Antibody-C-term - AP18171b from Abgent, a WuXi AppTec company
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MUDENG antibody - GTX53675 from GeneTex
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MUDEN Antibody - C-terminal region (OAAB13665) - OAAB13665 from Aviva Systems Biology
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Rabbit Anti-Human MUDEN (C-term) - 102-13712 from RayBiotech
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MUDEN antibody (C-term) - STJ46428 from St John's Laboratory Ltd
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Anti-AP5M1 (aa 355-384) polyclonal antibody - DPABH-10929 from Creative Diagnostics
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MUDEN, Polyclonal Antibody - MBS9206660 from MyBioSource
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MUDENG antibody - 26567-1-AP from Proteintech Group
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MUDEN Antibody - 59-693 from ProSci
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