| Gene Symbol |
AP5M1
|
| Entrez Gene |
55745
|
| Alt Symbol |
C14orf108, MUDENG, Mu5, MuD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adaptor-related protein complex 5, mu 1 subunit
|
| Other Description |
AP-5 complex subunit mu|AP-5 complex subunit mu-1|MHD domain-containing death-inducing protein|MU-2/AP1M2 domain containing, death-inducing|Mu-2 related death-inducing|adapter-related protein complex 5 mu subunit|adapter-related protein complex 5 subunit mu-1|adaptor-related protein complex 5 subunit mu-1|mu-2-related death-inducing protein|putative HIV-1 infection-related protein
|
| Swissprots |
Q96DX3 Q6ZMD7 Q9H0R1 O95354 Q9NVC5
|
| Accessions |
EAW80700 EAW80701 EAW80702 EAW80703 Q9H0R1 AF094583 AAC78130 AK001675 BAA91828 AK024921 AK172824 BAD18791 AK225345 AK303999 BAG64916 AL136685 CAB66620 BC013174 AAH13174 BQ000414 CN352262 DB204683 XM_006720196 XP_006720259 XM_011536940 XP_011535242 NM_018229 NP_060699 NR_026895
|
| Function |
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death. {ECO:0000269|PubMed:18395520, ECO:0000269|PubMed:22022230}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:22022230}. Late endosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Lysosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Note=May cycle on and off membranes.
|
| Tissue Specificity |
Expressed in various tumor cell lines including Jurkat, Hep-G2 and HeLa. {ECO:0000269|PubMed:18395520}.
|
