Gene Symbol | AP5M1 |
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Entrez Gene | 55745 |
Alt Symbol | C14orf108, MUDENG, Mu5, MuD |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 5, mu 1 subunit |
Other Description | AP-5 complex subunit mu|AP-5 complex subunit mu-1|MHD domain-containing death-inducing protein|MU-2/AP1M2 domain containing, death-inducing|Mu-2 related death-inducing|adapter-related protein complex 5 mu subunit|adapter-related protein complex 5 subunit mu-1|adaptor-related protein complex 5 subunit mu-1|mu-2-related death-inducing protein|putative HIV-1 infection-related protein |
Swissprots | Q96DX3 Q6ZMD7 Q9H0R1 O95354 Q9NVC5 |
Accessions | EAW80700 EAW80701 EAW80702 EAW80703 Q9H0R1 AF094583 AAC78130 AK001675 BAA91828 AK024921 AK172824 BAD18791 AK225345 AK303999 BAG64916 AL136685 CAB66620 BC013174 AAH13174 BQ000414 CN352262 DB204683 XM_006720196 XP_006720259 XM_011536940 XP_011535242 NM_018229 NP_060699 NR_026895 |
Function | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death. {ECO:0000269|PubMed:18395520, ECO:0000269|PubMed:22022230}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:22022230}. Late endosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Lysosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Note=May cycle on and off membranes. |
Tissue Specificity | Expressed in various tumor cell lines including Jurkat, Hep-G2 and HeLa. {ECO:0000269|PubMed:18395520}. |
MUDENG CRISPR/Cas9 KO Plasmid (h) - sc-405300 from Santa Cruz Biotechnology
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MUDENG HDR Plasmid (h) - sc-405300-HDR from Santa Cruz Biotechnology
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MUDENG Double Nickase Plasmid (h) - sc-405300-NIC from Santa Cruz Biotechnology
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MUDENG Double Nickase Plasmid (h2) - sc-405300-NIC-2 from Santa Cruz Biotechnology
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MUDENG CRISPR Activation Plasmid (h) - sc-405300-ACT from Santa Cruz Biotechnology
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MUDENG CRISPR Activation Plasmid (h2) - sc-405300-ACT-2 from Santa Cruz Biotechnology
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MUDENG Lentiviral Activation Particles (h) - sc-405300-LAC from Santa Cruz Biotechnology
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MUDENG Lentiviral Activation Particles (h2) - sc-405300-LAC-2 from Santa Cruz Biotechnology
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MUDENG siRNA (h) - sc-92214 from Santa Cruz Biotechnology
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MUDENG shRNA Plasmid (h) - sc-92214-SH from Santa Cruz Biotechnology
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MUDENG shRNA (h) Lentiviral Particles - sc-92214-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU042471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14764 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14764 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08470 from Sigma-Aldrich
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AP5M1 siRNA (Human) - CRJ0883 from Cohesion Biosciences
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AP5M1 - MBS8219249 from MyBioSource
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shRNA set against Human MUDENG (NM_018229.3) - SHH347008 from Creative biogene
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Human AP5M1 siRNA - orb271384 from Biorbyt
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AP5M1 shRNA Plasmid (Human) - CHJ0883 from Cohesion Biosciences
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AP5M1 miRNA 3'UTR clone - MiUTR3H-13231 from Creative biogene
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