PLIN5

Gene Symbol PLIN5
Entrez Gene 440503
Alt Symbol LSDA5, LSDP5, MLDP, OXPAT
Species Human
Gene Type protein-coding
Description perilipin 5
Other Description lipid storage droplet protein 5|perilipin-5
Swissprots Q6ZS68 A2RRC1 Q00G26
Accessions Q00G26 AW445065 BC033570 BC131524 AAI31525 BX105717 DQ839131 ABH07519 NM_001013706 NP_001013728
Function Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity). {ECO:0000250}.
Subcellular Location Lipid droplet {ECO:0000269|PubMed:17234449}. Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Lipid droplet surface-associated. Exchanges between lipid droplets and the cytoplasm (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in skeletal muscle, liver, heart and kidney. {ECO:0000269|PubMed:17234449}.

LSDP5 (E-3) - sc-514296 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LSDP5 (E-3): sc-514296. Western blot analysis of LSDP5 expression in non-transfected: sc-117752 (A) and mouse LSDP5 transfected: sc-121424 (B) 293T whole cell lysates.

LSDP5 (Q-14) - sc-240628 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LSDP5 (T-12) - sc-240627 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LSDP5 (T-12): sc-240627. Western blot analysis of LSDP5 expression in non-transfected: sc-117752 (A) and mouse LSDP5 transfected: sc-121424 (B) 293T whole cell lysates.

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa300-400, Biotin) - LS-C141669 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa300-400, DY650) - LS-C141670 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa300-400, DY488) - LS-C141671 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa300-400, HRP) - LS-C141672 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa300-400, DY550) - LS-C141673 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (C-Terminus, Biotin) - LS-C141674 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (C-Terminus, DY650) - LS-C141675 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (C-Terminus, DY488) - LS-C141676 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (C-Terminus, HRP) - LS-C141677 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (C-Terminus, DY550) - LS-C141678 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa451-463) - LS-C193732 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µl
Host Guinea Pig
Clonality Polyclonal

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa400-463) IHC-plus™ - LS-B5964 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PLIN5 / LSDP5 antibody IHC of mouse skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5964 concentration 5 ug/ml.

Anti-PLIN5 / OXPAT / LSDP5 Antibody (aa300-400) IHC-plus™ - LS-B2622 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PLIN5 / LSDP5 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2622 concentration 5 ug/ml.

OXPAT Antibody - NB110-60509 from Novus Biologicals

Prices $129.00, $349.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OXPAT Antibody [NB110-60509] - Detection of OXPAT in human (lane 1) and mouse (lane 2) heart lysate.

OXPAT Antibody - NB110-60511 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OXPAT Antibody [NB110-60511] - Detection of OXPAT in human (lane 1) and mouse (lane 2) heart lysate.

OXPAT Antibody [DyLight 650] - NB110-60509C from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXPAT Antibody [DyLight 488] - NB110-60509G from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXPAT Antibody [Biotin] - NB110-60509B from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXPAT Antibody [DyLight 550] - NB110-60509R from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXPAT Antibody [HRP] - NB110-60509H from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXPAT Antibody [Alexa Fluor (R) 647] - NB110-60509AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

OXPAT Antibody [Alexa Fluor (R) 488] - NB110-60509AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal
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