PLIN5

Gene Symbol PLIN5
Entrez Gene 440503
Alt Symbol LSDA5, LSDP5, MLDP, OXPAT
Species Human
Gene Type protein-coding
Description perilipin 5
Other Description lipid storage droplet protein 5|perilipin-5
Swissprots Q6ZS68 A2RRC1 Q00G26
Accessions Q00G26 AW445065 BC033570 BC131524 AAI31525 BX105717 DQ839131 ABH07519 NM_001013706 NP_001013728
Function Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity). {ECO:0000250}.
Subcellular Location Lipid droplet {ECO:0000269|PubMed:17234449}. Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Lipid droplet surface-associated. Exchanges between lipid droplets and the cytoplasm (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in skeletal muscle, liver, heart and kidney. {ECO:0000269|PubMed:17234449}.

LSDP5 CRISPR/Cas9 KO Plasmid (h) - sc-407240 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 HDR Plasmid (h) - sc-407240-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 Double Nickase Plasmid (h) - sc-407240-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 Double Nickase Plasmid (h2) - sc-407240-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 CRISPR Activation Plasmid (h) - sc-407240-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 CRISPR Activation Plasmid (h2) - sc-407240-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 Lentiviral Activation Particles (h) - sc-407240-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 Lentiviral Activation Particles (h2) - sc-407240-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LSDP5 siRNA (h) - sc-97411 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LSDP5 shRNA Plasmid (h) - sc-97411-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LSDP5 shRNA (h) Lentiviral Particles - sc-97411-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16986 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16986 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLIN5 siRNA (Human) - CRJ8252 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLIN (NM_001013706.2) - SHH377828 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LSDP5(NM_001013706.2) - SHH164711 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLIN5 siRNA - orb278753 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLIN5 shRNA Plasmid (Human) - CHJ8252 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLIN5 miRNA 3'UTR clone - MiUTR1H-05938 from Creative biogene

Species Reactivities Human
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