| Gene Symbol |
HIST1H4G
|
| Entrez Gene |
8369
|
| Alt Symbol |
H4/l, H4FL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H4g
|
| Other Description |
H4 histone family, member L|histone 1, H4g|histone H4-like protein type G
|
| Swissprots |
Q99525
|
| Accessions |
AAN01445 CAB02550 EAW55550 Q99525 BC126276 AAI26277 BC126278 AAI26279 HQ258035 ADR82789 NM_003547 NP_003538
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|
![Western Blot: HIST1H4G Overexpression Lysate (Adult Normal) [NBP2-07983] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HIST1H4G.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/24393_HIST1H4G%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-07983-img0001.jpg)