Gene Symbol | HIST1H4G |
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Entrez Gene | 8369 |
Alt Symbol | H4/l, H4FL |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H4g |
Other Description | H4 histone family, member L|histone 1, H4g|histone H4-like protein type G |
Swissprots | Q99525 |
Accessions | AAN01445 CAB02550 EAW55550 Q99525 BC126276 AAI26277 BC126278 AAI26279 HQ258035 ADR82789 NM_003547 NP_003538 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H4G CRISPR/Cas9 KO Plasmid (h) - sc-409711 from Santa Cruz Biotechnology
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Histone cluster 1 H4G HDR Plasmid (h) - sc-409711-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H4G Double Nickase Plasmid (h) - sc-409711-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H4G Double Nickase Plasmid (h2) - sc-409711-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H4G CRISPR Activation Plasmid (h) - sc-409711-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H4G CRISPR Activation Plasmid (h2) - sc-409711-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H4G Lentiviral Activation Particles (h) - sc-409711-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H4G Lentiviral Activation Particles (h2) - sc-409711-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H4G siRNA (h) - sc-95294 from Santa Cruz Biotechnology
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Histone cluster 1 H4G shRNA Plasmid (h) - sc-95294-SH from Santa Cruz Biotechnology
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Histone cluster 1 H4G shRNA (h) Lentiviral Particles - sc-95294-V from Santa Cruz Biotechnology
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HIST1H4G RNAi - H00008369-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10099 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10099 from Sigma-Aldrich
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HIST1H4G siRNA (Human) - CRH5489 from Cohesion Biosciences
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HIST1H4G - MBS8211218 from MyBioSource
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shRNA set against Human HIST1H4G (NM_003547.2) - SHH312821 from Creative biogene
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Human HIST1H4G siRNA - orb265991 from Biorbyt
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HIST1H4G shRNA Plasmid (Human) - CHH5489 from Cohesion Biosciences
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HIST1H4G miRNA 3'UTR clone - MiUTR1H-04559 from Creative biogene
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