Gene Symbol | PRKAR1A |
---|---|
Entrez Gene | 5573 |
Alt Symbol | ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1 |
Species | Human |
Gene Type | protein-coding |
Description | protein kinase, cAMP-dependent, regulatory, type I, alpha |
Other Description | Carney complex type 1|cAMP-dependent protein kinase regulatory subunit RIalpha|cAMP-dependent protein kinase type I-alpha regulatory chain|cAMP-dependent protein kinase type I-alpha regulatory subunit|protein kinase A type 1a regulatory subunit|tissue-specific extinguisher 1 |
Swissprots | K7ER48 Q567S7 P10644 |
Accessions | AAL05860 ABC96005 ABC96006 ABC96007 EAW89060 EAW89061 EAW89062 EAW89063 EAW89064 EAW89065 P10644 A12295 CAA01027 AA015682 AI074326 AK097580 BAG53489 AK124586 AK312307 BAG35232 AL050038 AL535889 AW732104 AY007115 BC036285 AAH36285 BC093042 AAH93042 BM928493 BU167718 BU188258 CR749311 CAH18166 DA108801 DA219203 DA413808 DQ891775 ABM82701 DQ894959 ABM85885 M18468 AAB50922 M33336 AAB50921 S54705 S54707 S54709 S54711 Y07642 CAA68925 XM_011524983 XP_011523285 XM_011524984 XP_011523286 XM_011524985 XP_011523287 NM_001276289 NP_001263218 NM_001276290 NP_001263219 NM_001278433 NP_001265362 NM_002734 NP_002725 NM_212471 NP_997636 NM_212472 NP_997637 |
Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. {ECO:0000269|PubMed:16491121, ECO:0000269|PubMed:20215566}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23115245}. |
Tissue Specificity | Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
Top Pathways | Apoptosis, Insulin signaling pathway |
PKA RI-α (D54D9) Rabbit mAb - 5675 from Cell Signaling Technology
|
||||||||||
PKA Iα reg (C-14) - sc-18800 from Santa Cruz Biotechnology
|
||||||||||
PKA Iα reg (N-15) - sc-18798 from Santa Cruz Biotechnology
|
||||||||||
PKA Iα reg (20) - sc-136231 from Santa Cruz Biotechnology
|
||||||||||
PKA Iα/β reg (B-6) - sc-271125 from Santa Cruz Biotechnology
|
||||||||||
PKA Iα/β reg (G-6) - sc-271446 from Santa Cruz Biotechnology
|
||||||||||
PKA Iα/β reg (H-90) - sc-28893 from Santa Cruz Biotechnology
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha (phospho S77) antibody [EPMAYR1] - ab139682 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha (phospho S83) antibody [EPMAYR1] - ab154851 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody - ab38936 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody - ab65013 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody [3546C2a] - ab60064 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody [6C7] - ab118061 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody [EPR8491] - ab139695 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody - N-terminal - ab180825 from Abcam
|
||||||||||
Anti-Protein Kinase A regulatory subunit I alpha antibody - N-terminal - ab195444 from Abcam
|
||||||||||
Anti-PRKAR1A Antibody - LS-C75190 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A / PKR1 Antibody - LS-C131711 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (clone 11C1062) - LS-C184098 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (clone 3546C2a) - LS-C184513 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (aa51-100) - LS-C151339 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (N-Terminus, APC) - LS-C226177 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (C-Terminus) - LS-C117130 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (N-Terminus, AP) - LS-C226178 from LifeSpan Bioscience
|
||||||||||
Anti-PRKAR1A Antibody (N-Terminus, Biotin) - LS-C226179 from LifeSpan Bioscience
|