Gene Symbol | PRKAR1A |
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Entrez Gene | 5573 |
Alt Symbol | ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1 |
Species | Human |
Gene Type | protein-coding |
Description | protein kinase, cAMP-dependent, regulatory, type I, alpha |
Other Description | Carney complex type 1|cAMP-dependent protein kinase regulatory subunit RIalpha|cAMP-dependent protein kinase type I-alpha regulatory chain|cAMP-dependent protein kinase type I-alpha regulatory subunit|protein kinase A type 1a regulatory subunit|tissue-specific extinguisher 1 |
Swissprots | K7ER48 Q567S7 P10644 |
Accessions | AAL05860 ABC96005 ABC96006 ABC96007 EAW89060 EAW89061 EAW89062 EAW89063 EAW89064 EAW89065 P10644 A12295 CAA01027 AA015682 AI074326 AK097580 BAG53489 AK124586 AK312307 BAG35232 AL050038 AL535889 AW732104 AY007115 BC036285 AAH36285 BC093042 AAH93042 BM928493 BU167718 BU188258 CR749311 CAH18166 DA108801 DA219203 DA413808 DQ891775 ABM82701 DQ894959 ABM85885 M18468 AAB50922 M33336 AAB50921 S54705 S54707 S54709 S54711 Y07642 CAA68925 XM_011524983 XP_011523285 XM_011524984 XP_011523286 XM_011524985 XP_011523287 NM_001276289 NP_001263218 NM_001276290 NP_001263219 NM_001278433 NP_001265362 NM_002734 NP_002725 NM_212471 NP_997636 NM_212472 NP_997637 |
Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. {ECO:0000269|PubMed:16491121, ECO:0000269|PubMed:20215566}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23115245}. |
Tissue Specificity | Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
Top Pathways | Apoptosis, Insulin signaling pathway |
Active human Protein Kinase A regulatory subunit I alpha full length protein - ab68967 from Abcam
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Human Protein Kinase A regulatory subunit I alpha full length protein - ab125532 from Abcam
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Protein Kinase A regulatory subunit I alpha peptide - ab41295 from Abcam
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PRKAR1A Antibody Blocking Peptide - LS-E25156 from LifeSpan Bioscience
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PRKAR1A Antibody Blocking Peptide - LS-E21141 from LifeSpan Bioscience
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PRKAR1A Antibody Blocking Peptide - LS-E9492 from LifeSpan Bioscience
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Recombinant Human Protein Kinase A regulatory subunit I alpha Protein - H00005573-P01 from Novus Biologicals
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Recombinant Human Protein Kinase A regulatory subunit I alpha Protein - H00005573-Q01 from Novus Biologicals
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Protein Kinase A regulatory subunit I alpha Peptide - P3101 from Novus Biologicals
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Protein-Kinase-A-regulatory-subunit-I-alpha-Antibody-N-term-Blocking-peptide - BP8095a from Abgent, a WuXi AppTec company
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PRKAR1A Protein (OPPA01115) - OPPA01115 from Aviva Systems Biology
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PKAR-I alpha Protein (OPPA01116) - OPPA01116 from Aviva Systems Biology
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Human PRKAR1A protein (His Tag) - orb139517 from Biorbyt
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PRKAR1A Blocking Peptide - 33R-6264 from Fitzgerald
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PRKAR1A Blocking Peptide - abx063125 from Abbexa
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PRKAR1A - H00005573-P01-10 from Acris Antibodies
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PRKAR1A - H00005573-P01-25 from Acris Antibodies
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PRKAR1A - H00005573-Q01-10 from Acris Antibodies
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PRKAR1A - H00005573-Q01-25 from Acris Antibodies
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Protein Kinase A regulatory subunit-1 alpha, Human Recombinant - 228-10221-1 from RayBiotech
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Recombinant Human PRKAR1 - 228-10221-2 from RayBiotech
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Recombinant Human PRKAR1 - 228-10221-3 from RayBiotech
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cAMP-Dependent Protein Kinase A regulatory subunit I a Recombinant - 228-11305-1 from RayBiotech
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Recombinant PRKA1RA - 228-11305-2 from RayBiotech
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Recombinant PRKA1RA - 228-11305-3 from RayBiotech
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