YOD1

Gene Symbol	YOD1
Entrez Gene	55432
Alt Symbol	DUBA8, OTUD2, PRO0907
Species	Human
Gene Type	protein-coding
Description	YOD1 deubiquitinase
Other Description	DUBA-8|HIN-7|HIV-1-induced protease 7|OTU domain containing 2|OTU domain-containing protein 2|YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)|hsHIN7|ubiquitin thioesterase OTU1
Swissprots	Q86T63 Q9P1L8 Q5VVQ5 B2RNX3 Q6ZRS6 Q5VVQ6
Accessions	EAW93509 Q5VVQ6 AK128014 BAC87233 AL833081 CAD89975 BC137166 AAI37167 BC137167 AAI37168 XM_011509725 XP_011508027 XR_247031 NM_001276320 NP_001263249 NM_018566 NP_061036
Function	Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. {ECO:0000269|PubMed:19818707, ECO:0000269|PubMed:23827681}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

OTUD2 CRISPR/Cas9 KO Plasmid (h) - sc-406672 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 HDR Plasmid (h) - sc-406672-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 Double Nickase Plasmid (h) - sc-406672-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 Double Nickase Plasmid (h2) - sc-406672-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 CRISPR Activation Plasmid (h) - sc-406672-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 CRISPR Activation Plasmid (h2) - sc-406672-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 Lentiviral Activation Particles (h) - sc-406672-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 Lentiviral Activation Particles (h2) - sc-406672-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 siRNA (h) - sc-76018 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

OTUD2 shRNA Plasmid (h) - sc-76018-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

OTUD2 shRNA (h) Lentiviral Particles - sc-76018-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU139001 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23017 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23017 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

YOD1 siRNA (Human) - CRJ0701 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

YOD1 RNAi - H00055432-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

YOD1 - MBS827841 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

OTUD2 CRISPR/Cas9 KO Plasmid (h2) - sc-406672-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

OTUD2 HDR Plasmid (h2) - sc-406672-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human Yod1 (NM_018566.3) - SHH448520 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human YOD1(NM_018566.3) - SHL140660 from Creative biogene Category siRNA Species Reactivities Human

Human YOD1 siRNA - orb271202 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

YOD1 shRNA Plasmid (Human) - CHJ0701 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

YOD1 miRNA 3'UTR clone - MiUTR1H-11339 from Creative biogene Species Reactivities Human

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