YOD1

Gene Symbol	YOD1
Entrez Gene	55432
Alt Symbol	DUBA8, OTUD2, PRO0907
Species	Human
Gene Type	protein-coding
Description	YOD1 deubiquitinase
Other Description	DUBA-8|HIN-7|HIV-1-induced protease 7|OTU domain containing 2|OTU domain-containing protein 2|YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)|hsHIN7|ubiquitin thioesterase OTU1
Swissprots	Q86T63 Q9P1L8 Q5VVQ5 B2RNX3 Q6ZRS6 Q5VVQ6
Accessions	EAW93509 Q5VVQ6 AK128014 BAC87233 AL833081 CAD89975 BC137166 AAI37167 BC137167 AAI37168 XM_011509725 XP_011508027 XR_247031 NM_001276320 NP_001263249 NM_018566 NP_061036
Function	Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. {ECO:0000269|PubMed:19818707, ECO:0000269|PubMed:23827681}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human YOD1 full length protein - ab125737 from Abcam Category Protein Source E. coli Species Human

Human YOD1 full length protein - ab140732 from Abcam Category Protein Source E. coli Species Human

YOD1 Antibody Blocking Peptide - LS-E905 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YOD1 Antibody Blocking Peptide - LS-E24517 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human YOD1 Protein - NBP2-22955 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

YOD1-Antibody-C-term-Blocking-peptide - BP11304b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human YOD1, CF - E-572-050 from R&D Systems Category Protein Source E. coli-derived,

Human YOD1 Enzyme - orb191418 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 2 μg, 10 μg, 100 μg Source Escherichia Coli. Species Human

YOD1 protein (His tag) - 80R-2723 from Fitzgerald Category Protein Prices $270.00 Sizes 20 µg Source E.coli

YOD1 (1-348, His-tag) - AR50843PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

YOD1 (1-348, His-tag) - AR50843PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

YOD1, 1-348aa, Human, His tag, E.coli - 01-P2019 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

YOD1 fusion protein - ag21881 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human YOD1, His-tagged - YOD1-7575H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human YOD1, GST-tagged - YOD1-177H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human YOD1, His-tagged - YOD1-175H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Ubiquitin thioesterase OTU1(YOD1) - CSB-YP713352HU CSB-EP713352HU CSB-BP713352HU CSB-MP713352HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human YOD1 Protein, CF - E-572 from R&D Systems Category Protein Prices $125.00 Sizes 50 µg Source E. coli -derived Species Human

YOD1/OTU1 - E-572 from Boston Biochem Prices $125.00 Sizes 50 µg

YOD1 (Recombinant) - abx073982 from Abbexa

YOD1, Recombinant Protein - MBS204930 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 20 µg, 100 µg Source E Coli Species Human

YOD1, Recombinant Protein - MBS146613 from MyBioSource Category Protein Prices $140.00, $205.00, $1,220.00 Sizes 2 µg, 10 µg, 100 µg Source E Coli

YOD1 Recombinant Protein Antigen - NBP1-84173PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

YOD1 Recombinant Protein Antigen - NBP1-84172PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

YOD1 Peptide, Human - M34GP17631H from Creative Peptides Category Peptide Source Synthetic. Species Human

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