SEMA7A

Gene Symbol SEMA7A
Entrez Gene 8482
Alt Symbol CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL
Species Human
Gene Type protein-coding
Description semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Other Description JMH blood group antigen|John Milton Hagen blood group H-Sema K1|john-Milton-Hargen human blood group Ag|sema K1|sema L|sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)|sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A|semaphorin K1|semaphorin L|semaphorin-7A|semaphorin-K1|semaphorin-L
Swissprots Q1XE81 B4DDP7 Q3MIY5 O75326 Q1XE82 F5H1S0 Q1XE83 Q1XE84
Accessions AAC34741 AAW62253 EAW99340 O75326 AF030698 AAC34261 AF069493 AAC82642 AF071542 AAC80456 AK001895 BAG50988 AK293280 BAG56808 AK312257 BAG35189 AM180445 CAJ55398 AM180446 CAJ55399 AM180447 CAJ55400 AM180448 CAJ55401 AM180449 CAJ55402 AM180450 CAJ55403 AM180451 CAJ55404 BC101643 AAI01644 BC101647 AAI01648 BU191525 DA136330 DC408557 NM_001146029 NP_001139501 NM_001146030 NP_001139502 NM_003612 NP_003603
Function Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. {ECO:0000269|PubMed:12879062, ECO:0000269|PubMed:17377534, ECO:0000269|PubMed:17671519}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10201933, ECO:0000269|PubMed:17671519, ECO:0000269|PubMed:9712866}; Lipid- anchor, GPI-anchor {ECO:0000269|PubMed:10201933, ECO:0000269|PubMed:17671519, ECO:0000269|PubMed:9712866}; Extracellular side {ECO:0000269|PubMed:10201933, ECO:0000269|PubMed:17671519, ECO:0000269|PubMed:9712866}. Note=Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
Tissue Specificity Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney. {ECO:0000269|PubMed:10201933, ECO:0000269|PubMed:17671519, ECO:0000269|PubMed:9712866}.
Top Pathways Axon guidance

Human SEMA7A / Semaphorin 7A ELISA Kit (Sandwich ELISA) - LS-F6575 from LifeSpan Bioscience

Category ELISA Kit
Prices $690.00
Sizes 1 plate
Sensitivity 0.156 ng/ml
Range 0.156-10 ng/ml

Mouse SEMA7A / Semaphorin 7A ELISA Kit (Sandwich ELISA) - LS-F6958 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity 0.313 ng/ml
Range 0.156-10 ng/ml

Semaphorin 7A, SEMA7A, Human, ELISA Kit - E-EL-H1074 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

Semaphorin 7A (SEMA7A), Human, ELISA Kit - SEB448Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 0.059ng/mL
Range 0.156-10ng/mL

Semaphorin-7A (SEMA7A), Human, ELISA Kit - CSB-EL021000HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Semaphorin-7A, SEMA7A, Human, ELISA Kit - E2274h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t

Semaphorin 7A, SEMA7A, Mouse, ELISA Kit - E-EL-M1043 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Semaphorin 7A, SEMA7A, Rat, ELISA Kit - E-EL-R0879 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Semaphorin 7A, SEMA7A, Rabbit, ELISA Kit - E-EL-RB1783 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Semaphorin 7A, SEMA7A, Chicken, ELISA Kit - E-EL-Ch2097 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Semaphorin 7A, SEMA7A, Porcine, ELISA Kit - E-EL-P1879 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Semaphorin 7A, SEMA7A, Guinea Pig, ELISA Kit - E-EL-GP0702 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Semaphorin 7A, SEMA7A, Monkey, ELISA Kit - E-EL-MK1947 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Custom Human Semaphorin 7A ELISA - ELH-SEMA7A from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human SEMA7A ELISA Kit - HS0090 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine SEMA7A ELISA Kit - AS0090 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Human SEMA7A(Semaphorin 7A) ELISA Kit - E-EL-H1074 from Elabscience

Category ELISA Kit
Sensitivity 0.10 ng/mL
Range 0.16—10 ng/mL

Human SEMA7A (Semaphorin 7A) CLIA Kit - E-CL-H0721 from Elabscience

Category CLIA Kit
Sensitivity 18.75 pg/mL
Range Average Recovery (%)

SEMA7A, ELISA Kit - MBS2503689 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.375ng/mL
Range 0.625-40ng/mL

SEMA7A, ELISA Kit - MBS2514698 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.875ng/mL
Range 3.125-200ng/mL

SEMA7A, ELISA Kit - MBS2510925 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.875ng/mL
Range 3.125-200ng/mL

SEMA7A, ELISA Kit - MBS2503009 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/mL
Range 0.156--10ng/mL

SEMA7A, ELISA Kit - MBS2508188 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/mL
Range 0.313--20ng/mL

SEMA7A, ELISA Kit - MBS2511804 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/mL
Range 0.156-10ng/mL

SEMA7A, ELISA Kit - MBS2512065 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/mL
Range 0.313--20ng/mL
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