Gene Symbol | Car2 |
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Entrez Gene | 12349 |
Alt Symbol | AI131712, CAII, Ca2, Car-2, Ltw-5, Lvtw-5 |
Species | Mouse |
Gene Type | protein-coding |
Description | carbonic anhydrase 2 |
Other Description | CA II|CA-II|carbonate dehydratase II|carbonic anhydrase II |
Swissprots | Q9DCY9 Q7TPE1 Q9DCT3 P00920 Q6LDQ7 |
Accessions | AAA37357 EDL05130 P00920 AK002333 BAB22019 AK002498 BAB22146 AK146015 BC044806 BC055291 AAH55291 BU946040 CD774528 K00811 AAA37356 M25944 AAA39505 U37705 U37706 XM_006530050 XP_006530113 NM_009801 NP_033931 |
Function | Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000269|PubMed:20150244}. |
Subcellular Location | Cytoplasm. Cell membrane {ECO:0000250}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells (By similarity). {ECO:0000250}. |
Top Pathways | Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion |
Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) - 139548 from USBiological Life Science
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Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) (AP) - 139548-AP from USBiological Life Science
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Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) (APC) - 139548-APC from USBiological Life Science
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Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) (Biotin) - 139548-Biotin from USBiological Life Science
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Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) (FITC) - 139548-FITC from USBiological Life Science
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Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) (HRP) - 139548-HRP from USBiological Life Science
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Anti -CA2 (Carbonic Anhydrase 2, Carbonate Dehydratase II, Carbonic Anhydrase C, CarbonicAnhydrase II) (PE) - 139548-PE from USBiological Life Science
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CA II antibody - orb170547 from Biorbyt
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Carbonic Anhydrase II Antibody - abx101965 from Abbexa
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Anti-Carbonic Anhydrase II (CA2) - 20-3161 from ARP American Research Products
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2001985 from MyBioSource
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2002168 from MyBioSource
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2016276 from MyBioSource
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Carbonic Anhydrase II Antibody, Rabbit PAb - 50685-RP01-100 from Sino Biological
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Carbonic Anhydrase II / Car2 Antibody, Rabbit PAb, Antigen Affinity Purified - 50685-RP02-50 from Sino Biological
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Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb - 50685-R002-50 from Sino Biological
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Carbonic Anhydrase II / Car2 Antibody, Rabbit MAb - 50685-R003-50 from Sino Biological
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Polyclonal Antibody to Carbonic Anhydrase II (CA2) - PAA782Mu01 from Cloud-clone
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Biotin-Linked Antibody to Carbonic Anhydrase II (CA2) - PAA782Mu71 from Cloud-clone
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Carbonic Anhydrase II antibody - orb231589 from Biorbyt
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Carbonic Anhydrase II (CA2) Polyclonal Antibody - CAU27157 from Biomatik
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2047343 from MyBioSource
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2047344 from MyBioSource
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2047345 from MyBioSource
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Carbonic Anhydrase II (CA2), Polyclonal Antibody - MBS2047346 from MyBioSource
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