Gene Symbol | Car2 |
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Entrez Gene | 12349 |
Alt Symbol | AI131712, CAII, Ca2, Car-2, Ltw-5, Lvtw-5 |
Species | Mouse |
Gene Type | protein-coding |
Description | carbonic anhydrase 2 |
Other Description | CA II|CA-II|carbonate dehydratase II|carbonic anhydrase II |
Swissprots | Q9DCY9 Q7TPE1 Q9DCT3 P00920 Q6LDQ7 |
Accessions | AAA37357 EDL05130 P00920 AK002333 BAB22019 AK002498 BAB22146 AK146015 BC044806 BC055291 AAH55291 BU946040 CD774528 K00811 AAA37356 M25944 AAA39505 U37705 U37706 XM_006530050 XP_006530113 NM_009801 NP_033931 |
Function | Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000269|PubMed:20150244}. |
Subcellular Location | Cytoplasm. Cell membrane {ECO:0000250}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells (By similarity). {ECO:0000250}. |
Top Pathways | Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion |
Carbonic anhydrase 2, Ca2, Mouse, ELISA Kit - E0782m from ARP American Research Products
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Carbonic Anhydrase II, Mouse, ELISA Kit - E03C0621 from ARP American Research Products
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Mouse CA2 ELISA Kit - MC0628 from NeoScientific
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Carbonic Anhydrase II (CA2), ELISA Kit - MBS265064 from MyBioSource
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Mouse CA2(Carbonic Anhydrase Ⅱ) ELISA Kit - E-EL-M0229 from Elabscience
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Mouse CA2 (Carbonic Anhydrase 2) CLIA Kit - E-CL-M0165 from Elabscience
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Carbonic anhydrase 2, ELISA Kit - MBS281372 from MyBioSource
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Carbonic Anhydrase II, ELISA Kit - MBS037414 from MyBioSource
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Mouse Carbonic Anhydrase II ELISA - E03C0621 from BlueGene Biotech
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Mouse CA2(Carbonic Anhydrase II) ELISA Kit - E-EL-M0229 from Iwai North America Inc.
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Mouse ADP/Acrp30 (Adiponectin) CLIA Kit - E-CL-M0002 from Iwai North America Inc.
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Mouse CA2 (Carbonic Anhydrase 2) CLIA Kit - E-CL-M0165 from Iwai North America Inc.
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Mouse Carbonic Anhydrase 2 ELISA Kit - abx052918 from Abbexa
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Mouse Carbonic Anhydrase 2 ELISA Kit - abx255230 from Abbexa
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CA2 - EKM1780 from Nordic BioSite
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Mouse Ca2 ELISA Kit - E046447 from Biobool
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Mouse CA-2 ELISA Kit - E046941 from Biobool
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Mouse Anti-CA2 ELISA Kit - E046964 from Biobool
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CA2 ELISA Kit (Mouse) (OKEH05770) - OKEH05770 from Aviva Systems Biology
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Mouse CA2 ELISA Kit - EMC0628 from ABclonal
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Carbonic anhydrase 2, ELISA Kit - MBS2885611 from MyBioSource
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