| Gene Symbol |
NPY4R
|
| Entrez Gene |
5540
|
| Alt Symbol |
NPY4-R, PP1, PPYR1, Y4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropeptide Y receptor Y4
|
| Other Description |
neuropeptide Y receptor type 4|pancreatic polypeptide receptor 1
|
| Swissprots |
Q5ISU3 Q6FH06 P50391 Q5T2X9 Q13456
|
| Accessions |
AAC50280 AAP23199 CAA91433 CAG26290 CAI13318 CAV09711 CAV28326 P50391 AY649985 AAV68196 AY649986 AAV68197 BC096238 AAH96238 BC099637 AAH99637 CR541950 CAG46748 U42387 AAB07759 XM_011539928 XP_011538230 XM_011539929 XP_011538231 XM_011539930 XP_011538232 XM_011539931 XP_011538233 XM_011539932 XP_011538234 XM_011539933 XP_011538235 XM_011539934 XP_011538236 XM_011539935 XP_011538237 XM_011539936 XP_011538238 XM_011539937 XP_011538239 NM_001278794 NP_001265723 NM_005972 NP_005963
|
| Function |
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|