Gene Symbol | NPY4R |
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Entrez Gene | 5540 |
Alt Symbol | NPY4-R, PP1, PPYR1, Y4 |
Species | Human |
Gene Type | protein-coding |
Description | neuropeptide Y receptor Y4 |
Other Description | neuropeptide Y receptor type 4|pancreatic polypeptide receptor 1 |
Swissprots | Q5ISU3 Q6FH06 P50391 Q5T2X9 Q13456 |
Accessions | AAC50280 AAP23199 CAA91433 CAG26290 CAI13318 CAV09711 CAV28326 P50391 AY649985 AAV68196 AY649986 AAV68197 BC096238 AAH96238 BC099637 AAH99637 CR541950 CAG46748 U42387 AAB07759 XM_011539928 XP_011538230 XM_011539929 XP_011538231 XM_011539930 XP_011538232 XM_011539931 XP_011538233 XM_011539932 XP_011538234 XM_011539933 XP_011538235 XM_011539934 XP_011538236 XM_011539935 XP_011538237 XM_011539936 XP_011538238 XM_011539937 XP_011538239 NM_001278794 NP_001265723 NM_005972 NP_005963 |
Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human NPY4R full length protein - ab159179 from Abcam
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NPY4R / PPYR1 Antibody Blocking Peptide - LS-E3098 from LifeSpan Bioscience
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NPY4R / PPYR1 Antibody Blocking Peptide - LS-E28120 from LifeSpan Bioscience
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NPY4R / PPYR1 Antibody Blocking Peptide - LS-E28122 from LifeSpan Bioscience
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NPY4R / PPYR1 Antibody Blocking Peptide - LS-E28121 from LifeSpan Bioscience
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NPY4R / PPYR1 Antibody Blocking Peptide - LS-E24186 from LifeSpan Bioscience
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Recombinant Human NPY4R Protein - H00005540-P01 from Novus Biologicals
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Recombinant Human NPY4R Protein - H00005540-G01 from Novus Biologicals
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NPY4R Recombinant Protein - H00005540-G02 from Novus Biologicals
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PPYR1-Antibody-N-term-Blocking-Peptide - BP14238a from Abgent, a WuXi AppTec company
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PP-1 peptide - orb73144 from Biorbyt
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NPY receptor 4 / NPY4R - H00005540-G01 from Acris Antibodies
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NPY receptor 4 / NPY4R - H00005540-G02 from Acris Antibodies
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NPY receptor 4 / NPY4R - H00005540-P01-10 from Acris Antibodies
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NPY receptor 4 / NPY4R - H00005540-P01-25 from Acris Antibodies
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PPYR1 fusion protein - Ag16952 from Proteintech Group
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PPYR1 fusion protein - Ag16374 from Proteintech Group
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Recombinant Human PPYR1, His-tagged - PPYR1-1932H from Creative Biomart
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PP1 Protein, purified, 10 units - 14-110 from EMD Millipore
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ChemiSCREEN™ Membrane Preparation Recombinant Human Y 4 Neuropeptide Y Receptor - HTS204M from EMD Millipore
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PP1 (FL) - sc-4291 from Santa Cruz Biotechnology
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NPY4R Protein - abx163104 from Abbexa
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PPYR1 Peptide, Human - M34GP12305H from Creative Peptides
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NPY4R Recombinant Protein Antigen - NBP1-82534PEP from Novus Biologicals
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Neuropeptide Y receptor type 4 (PPYR1), Recombinant Protein - MBS964044 from MyBioSource
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