KCNQ4

Gene Symbol KCNQ4
Entrez Gene 9132
Alt Symbol DFNA2, DFNA2A, KV7.4
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated KQT-like subfamily Q, member 4
Other Description potassium channel KQT-like 4|potassium channel subunit alpha KvLQT4|potassium voltage-gated channel subfamily KQT member 4|potassium voltage-gated channel, KQT-like subfamily, member 4
Swissprots O96025 P56696
Accessions AAD14681 EAX07197 P56696 AF105202 AAD14680 AK074957 BAG52040 CA411644 DA782056 XM_011542417 XP_011540719 XM_011542418 XP_011540720 XM_011542419 XP_011540721 XM_011542420 XP_011540722 XR_946798 XR_946799 XR_946800 NM_004700 NP_004691 NM_172163 NP_751895
Function Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.
Subcellular Location Basal cell membrane; Multi-pass membrane protein. Note=Situated at the basal membrane of cochlear outer hair cells. {ECO:0000250}.
Tissue Specificity Expressed in the outer, but not the inner, sensory hair cells of the cochlea. Slightly expressed in heart, brain and skeletal muscle.

KCNQ4 CRISPR/Cas9 KO Plasmid (h) - sc-403090 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 HDR Plasmid (h) - sc-403090-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 Double Nickase Plasmid (h) - sc-403090-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 Double Nickase Plasmid (h2) - sc-403090-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 CRISPR Activation Plasmid (h) - sc-403090-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 CRISPR Activation Plasmid (h2) - sc-403090-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 Lentiviral Activation Particles (h) - sc-403090-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 Lentiviral Activation Particles (h2) - sc-403090-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 siRNA (h) - sc-42503 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCNQ4 shRNA Plasmid (h) - sc-42503-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCNQ4 shRNA (h) Lentiviral Particles - sc-42503-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Kv7.4 RNAi - H00009132-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Kv7.4 RNAi - H00009132-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU122991 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10989 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10989 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00767 from Sigma-Aldrich

Category miRNA

KCNQ4 siRNA (Human) - CRH6039 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNQ4 CRISPR/Cas9 KO Plasmid (h2) - sc-403090-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCNQ4 HDR Plasmid (h2) - sc-403090-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human KCNQ4 (NM_004700.3) - SHH323679 from Creative biogene

Category siRNA
Species Reactivities Human

Human KCNQ4 siRNA - orb266541 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNQ4 shRNA Plasmid (Human) - CHH6039 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNQ4 miRNA 3'UTR clone - MiUTR4H-TG04726 from Creative biogene

Species Reactivities Human
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