KCNQ4

Gene Symbol KCNQ4
Entrez Gene 9132
Alt Symbol DFNA2, DFNA2A, KV7.4
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated KQT-like subfamily Q, member 4
Other Description potassium channel KQT-like 4|potassium channel subunit alpha KvLQT4|potassium voltage-gated channel subfamily KQT member 4|potassium voltage-gated channel, KQT-like subfamily, member 4
Swissprots O96025 P56696
Accessions AAD14681 EAX07197 P56696 AF105202 AAD14680 AK074957 BAG52040 CA411644 DA782056 XM_011542417 XP_011540719 XM_011542418 XP_011540720 XM_011542419 XP_011540721 XM_011542420 XP_011540722 XR_946798 XR_946799 XR_946800 NM_004700 NP_004691 NM_172163 NP_751895
Function Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.
Subcellular Location Basal cell membrane; Multi-pass membrane protein. Note=Situated at the basal membrane of cochlear outer hair cells. {ECO:0000250}.
Tissue Specificity Expressed in the outer, but not the inner, sensory hair cells of the cochlea. Slightly expressed in heart, brain and skeletal muscle.

KCNQ4 (F-10) - sc-271320 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KCNQ4 (F-10): sc-271320. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

KCNQ4 (G-14) - sc-20882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

KCNQ4 (H-130) - sc-50417 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KCNQ4 (H-130): sc-50417. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic and membrane staining of myocytes.

KCNQ4 (S-18) - sc-12442 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KCNQ4 (S-18): sc-12442. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing membrane and cytoplasmic staining of cells in seminiferous ducts.

Anti-KCNQ4 antibody - ab65797 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ4 antibody - ab110373 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNQ4 antibody - ab82096 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-KCNQ4 antibody (ab82096) at 2 µg/ml + Human Cerebellum lysate (in RIPA buffer). at 35 µgdeveloped using the ECL technique

Anti-KCNQ4 antibody - ab56456 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KCNQ4 antibody [S43-6] - ab84820 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6
ab84820 staining KCNQ4 in KCNQ4 transfected NIH3T3 cell line by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with 4% PFA, permeabilized with 0.5% Triton X-100 in PBS and blocked with 4% Milk in PBS for 60 minutes at 21°C. Samples were incubated with primary antibody (1/1000 in PBS) for 1 hour at 21°C. An Alexa Fluor®594-conjugated Goat anti-mouse IgG polyclonal (1/500) was used as the secondary antibody.See Abreview

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, SA) - LS-C230721 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (aa596-696) - LS-C308602 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KCNQ4 Antibody (aa650-695) - LS-C313806 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNQ4 Antibody (aa596-696, Azide-free) - LS-C327703 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-KCNQ4 Antibody (aa2-77, clone S43-6) - LS-C109008 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6
IHC analysis of KCNQ4 in frozen sections of mouse brain extract using KCNQ4 antibody.

Anti-KCNQ4 Antibody - LS-C123930 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-KCNQ4 Antibody - LS-C130329 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KCNQ4 Antibody (N-Terminus) - LS-C144756 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNQ4 Antibody (clone S43-6) - LS-C152676 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, Atto 488) - LS-C230706 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (N-Terminus) - LS-C153517 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, Atto 390) - LS-C230704 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, Atto 565) - LS-C230707 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, Atto 594) - LS-C230708 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, Atto 633) - LS-C230709 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6

Anti-KCNQ4 Antibody (aa2-77, clone S43-6, Atto 680) - LS-C230711 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S43-6
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