TICRR

Gene Symbol TICRR
Entrez Gene 90381
Alt Symbol C15orf42, SLD3, Treslin
Species Human
Gene Type protein-coding
Description TOPBP1-interacting checkpoint and replication regulator
Other Description topBP1-interacting replication-stimulating protein|treslin
Swissprots Q7Z2Z1 Q9BU55 Q8NCH6 Q8N4X8 B3KVV9 D3IUT4 B2RE07
Accessions CAF86784 EAX02056 Q7Z2Z1 AK074727 BAC11165 AK123612 BAG53921 AK315750 BAG38104 AW627706 BC002881 AAH02881 BC033209 AAH33209 BX538335 CAD98102 CN285632 DR731357 DR731358 GQ227787 ADC30133 XM_011522161 XP_011520463 XM_011522162 XP_011520464 NM_001308025 NP_001294954 NM_152259 NP_689472
Function Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre- initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. {ECO:0000269|PubMed:20116089}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20080954}. Note=Associates with chromatin.

Anti-C15orf42 antibody - ab124268 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C15orf42 antibody (ab124268) at 1/1000 dilutionLane 1 : 293 whole cell lysate treated with control siLUC RNAiLane 2 : 293 whole cell lysate treated with RNAi targeting C15orf42Lane 3 : 293 whole cell lysate treated with RNAi targeting C15orf42Lysates/proteins at 50 µg per lane.SecondaryDonkey Anti-Rabbit IgG H&L (HRP) (ab16284) at 1/20000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-C15orf42 antibody - C-terminal - ab191850 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-C15orf42 antibody - C-terminal (ab191850) at 1 µg/ml + Human small intestine tissue lysate at 15 µgdeveloped using the ECL technique

Anti-C15orf42 antibody - N-terminal - ab190182 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C15orf42 antibody - N-terminal (ab190182) at 1/2000 dilutionLane 1 : Human U2OS cell lysateLane 2 : Human U2OS cell lysate transfected with C15orf42 siRNALane 3 : Mouse embryo fibroblasts (MEFs) cell lysateLane 4 : Rat INS1 cell lysateLysates/proteins at 30 µg per lane.

Anti-TICRR Antibody (aa975-1025) - LS-C290143 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Treslin by Western Blot. Samples: Whole cell lysate (15 and 50 ug) from 293T cells. Antibodies: Affinity purified rabbit anti-Treslin antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-TICRR Antibody (C-Terminus) IHC-plus™ - LS-B12147 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

TICRR Antibody - NBP2-41283 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TICRR Antibody [NBP2-41283] - Western blot analysis of TICRR in human small intestine tissue lysate with TICRR antibody at 1 ug/ml.

C15orf42 antibody - H00090381-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

TICRR Antibody - 7857 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TICRR in human small intestine tissue lysate with TICRR antibody at 1 μg/ml.

Treslin Antibody - A303-472A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

Anti-TICRR (aa 975-1025) polyclonal antibody - DPABH-21930 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

TICRR, Polyclonal Antibody - MBS153502 from MyBioSource

Prices $140.00, $355.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal

C15orf42, Polyclonal Antibody - MBS540790 from MyBioSource

Prices $390.00
Sizes 0.1 mg affinity-purified
Host Rabbit
Clonality Polyclonal

TICRR Antibody - 600-401-FE3 from Rockland Immunochemicals Inc

Prices $319.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

C15orf42 Antibody - TRSLN-101AP from FabGennix

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TICRR-Antibody-C-Terminus-ALS16435 - ALS16435 from Abgent, a WuXi AppTec company

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

Treslin (N-19) - sc-245353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Treslin Polyclonal Antibody - PA5-38053 from Thermo Fisher Scientific

Prices $309.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Treslin in human small intestine tissue lysate using a Treslin polyclonal antibody (Product # PA5-38053) at a dilution of 1ug/ml.

TICRR-Antibody - ASC11813 from Abgent, a WuXi AppTec company

Prices $320.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TICRR in human small intestine tissue lysate with TICRR antibody at 1 µg/ml.

Treslin / TICRR antibody - TA349061 from Acris Antibodies

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TICRR in human small intestine tissue lysate with TICRR antibody at 1 ug/mL.

TICRR (C-Terminus) antibody - pab77534 from Covalab

Host Rabbit
Clonality Polyclonal

C15orf42, Polyclonal Antibody - MBS5400181 from MyBioSource

Prices $495.00
Sizes 0.1 mg biotin
Host Rabbit
Clonality Polyclonal

C15orf42, Polyclonal Antibody - MBS5400182 from MyBioSource

Prices $495.00
Sizes 0.1 mg fitc
Host Rabbit
Clonality Polyclonal

TICRR , Polyclonal Antibody - MBS2400031 from MyBioSource

Prices $495.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TICRR antibody - orb386971 from Biorbyt

Host Rabbit
Clonality Polyclonal

TICRR antibody - orb243977 from Biorbyt

Host Rabbit
Clonality Polyclonal
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