TICRR

Gene Symbol TICRR
Entrez Gene 90381
Alt Symbol C15orf42, SLD3, Treslin
Species Human
Gene Type protein-coding
Description TOPBP1-interacting checkpoint and replication regulator
Other Description topBP1-interacting replication-stimulating protein|treslin
Swissprots Q7Z2Z1 Q9BU55 Q8NCH6 Q8N4X8 B3KVV9 D3IUT4 B2RE07
Accessions CAF86784 EAX02056 Q7Z2Z1 AK074727 BAC11165 AK123612 BAG53921 AK315750 BAG38104 AW627706 BC002881 AAH02881 BC033209 AAH33209 BX538335 CAD98102 CN285632 DR731357 DR731358 GQ227787 ADC30133 XM_011522161 XP_011520463 XM_011522162 XP_011520464 NM_001308025 NP_001294954 NM_152259 NP_689472
Function Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre- initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. {ECO:0000269|PubMed:20116089}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20080954}. Note=Associates with chromatin.

MISSION® esiRNA - EHU080401 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4382 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4382 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TICRR siRNA (Human) - CRJ3939 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Treslin CRISPR/Cas9 KO Plasmid (h) - sc-409351 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Treslin HDR Plasmid (h) - sc-409351-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C15orf42 Double Nickase Plasmid (h) - sc-409351-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Treslin Double Nickase Plasmid (h2) - sc-409351-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C15orf42 CRISPR Activation Plasmid (h) - sc-409351-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Treslin CRISPR Activation Plasmid (h2) - sc-409351-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C15orf42 Lentiviral Activation Particles (h) - sc-409351-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Treslin Lentiviral Activation Particles (h2) - sc-409351-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Treslin siRNA (h) - sc-90086 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Treslin shRNA Plasmid (h) - sc-90086-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Treslin shRNA (h) Lentiviral Particles - sc-90086-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TICRR - MBS8226730 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C15orf42 (NM_152259.3) - SHH249562 from Creative biogene

Category siRNA
Species Reactivities Human

Human TICRR siRNA - orb274440 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TICRR shRNA Plasmid (Human) - CHJ3939 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TICRR miRNA 3'UTR clone - MiUTR1H-01135 from Creative biogene

Species Reactivities Human
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