| Gene Symbol |
THRSP
|
| Entrez Gene |
7069
|
| Alt Symbol |
LPGP1, Lpgp, S14, SPOT14, THRP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thyroid hormone responsive
|
| Other Description |
SPOT14 homolog|lipogenic protein 1|spot 14 protein|thyroid hormone responsive (SPOT14 homolog, rat)|thyroid hormone responsive SPOT14|thyroid hormone-inducible hepatic protein
|
| Swissprots |
B2R4W7 Q92748
|
| Accessions |
CAA69685 EAW75045 Q92748 AI480357 AI749106 AK311975 BAG34914 BC031989 AAH31989 BG674197 BP317892 CB122257 EU447014 ABZ92543 NM_003251 NP_003242
|
| Function |
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. {ECO:0000250, ECO:0000269|PubMed:17418816, ECO:0000269|PubMed:18299245}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:18299245}. Cytoplasm {ECO:0000269|PubMed:18299245}.
|
| Tissue Specificity |
Mainly expressed in tissues that synthesize triglycerides.
|
![Western Blot: THRSP Overexpression Lysate (Adult Normal) [NBL1-16897] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for THRSP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6666_THRSP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16897-img0002.jpg)