THRSP

Gene Symbol THRSP
Entrez Gene 7069
Alt Symbol LPGP1, Lpgp, S14, SPOT14, THRP
Species Human
Gene Type protein-coding
Description thyroid hormone responsive
Other Description SPOT14 homolog|lipogenic protein 1|spot 14 protein|thyroid hormone responsive (SPOT14 homolog, rat)|thyroid hormone responsive SPOT14|thyroid hormone-inducible hepatic protein
Swissprots B2R4W7 Q92748
Accessions CAA69685 EAW75045 Q92748 AI480357 AI749106 AK311975 BAG34914 BC031989 AAH31989 BG674197 BP317892 CB122257 EU447014 ABZ92543 NM_003251 NP_003242
Function Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. {ECO:0000250, ECO:0000269|PubMed:17418816, ECO:0000269|PubMed:18299245}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18299245}. Cytoplasm {ECO:0000269|PubMed:18299245}.
Tissue Specificity Mainly expressed in tissues that synthesize triglycerides.

Spot 14 (B-6) - sc-390939 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Spot 14 (B-6): sc-390939. Western blot analysis of Spot 14 expression in non-transfected: sc-117752 (A) and mouse Spot 14 transfected: sc-110387 (B) 293T whole cell lysates.

Spot 14 (D-2) - sc-390953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Spot 14 (D-2): sc-390953. Western blot analysis of Spot 14 expression in non-transfected: sc-117752 (A) and mouse Spot 14 transfected: sc-110387 (B) 293T whole cell lysates.

Spot 14 (L-16) - sc-66657 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Spot 14 (D-15) - sc-66655 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Spot 14 (D-15): sc-66655. Western blot analysis of Spot 14 expression in non-transfected: sc-117752 (A) and mouse Spot 14 transfected: sc-110387 (B) 293T whole cell lysates.

Spot 14 (H-57) - sc-67299 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Spot 14 (H-57): sc-67299. Western blot analysis of Spot 14 expression in non-transfected: sc-117752 (A) and human Spot 14 transfected: sc-113757 (B) 293T whole cell lysates.

Spot 14 (F-7) - sc-137178 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Spot 14 (F-7): sc-137178. Western blot analysis of Spot 14 expression in non-transfected: sc-117752 (A) and human Spot 14 transfected: sc-113757 (B) 293T whole cell lysates.

Anti-THRSP antibody - ab97504 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of THRSP staining in human breast adipose frozen tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab97504, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-THRSP antibody - ab111011 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111011, at 3.75µg/ml, staining THRSP in Formalin-fixed, Paraffin-embedded Human breast tissue by Immunohistochemistry.

Anti-THRSP Antibody (N-Terminus) - LS-C47014 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THRSP Antibody - LS-C346296 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using THRSP antibody. Blue: DAPI for nuclear staining.

Anti-THRSP Antibody (clone 2F8) - LS-C133959 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8
Detection limit for recombinant GST tagged THRSP is 0.3 ng/ml as a capture antibody.

Anti-THRSP Antibody IHC-plus™ - LS-B3813 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-THRSP antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3813 concentration 3.75 ug/ml.

THRSP Antibody - NBP1-81290 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: THRSP Antibody [NBP1-81290] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.

THRSP Antibody - NBP1-52541 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: THRSP Antibody [NBP1-52541] - Analysis of anti-THRSP antibody with human breast at concentration 3.75 ug/ml.

THRSP Antibody (2F8) - H00007069-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8

THRSP Polyclonal Antibody - bs-6738R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Squamous cell carcinoma stained with Anti-THRSP (bs-6738R)

Monoclonal Anti-THRSP, (N-terminal) antibody produced in mouse - SAB1402374 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8
<B>Immunohistochemistry</B><BR/>Monoclonal Anti-THRSP, antibody produced in mouse, clone 2F8, purified immunoglobulin: <B>Cat. No. SAB1402374</B>: Antibody concentration: 3 μg/mL using human salivary gland tissue.

Anti-THRSP antibody produced in rabbit - HPA040642 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-THRSP: <B>Cat. No. HPA040642</B>: Immunohistochemical staining of human cerebral cortex shows strong granular cytoplasmic positivity in neuronal cells.

Anti-THRSP (71-82) antibody produced in rabbit - SAB1100939 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-THRSP (71-82) : <B>Cat. No. SAB1100939</B>: Immunofluorescence of HUVEC cells using THRSP (71-82) , Cat. No. SAB1100939 (red) at a 1:200 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-THRSP (133-145) antibody produced in rabbit - SAB1100940 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-THRSP (133-145) : <B>Cat. No. SAB1100940</B>: Immunofluorescence of HUVEC cells using THRSP (133-145) , Cat. No. SAB1100940 (red) at a 1:50 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Mouse THRSP Antibody - AF6574 from R&D Systems

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat
Detection of Mouse THRSP by Western Blot. Western blot shows lysates of mouse liver tissue. PVDF Membrane was probed with 0.5 µg/mL of Mouse THRSP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6574) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109 ). A specific band was detected for THRSP at approximately 20 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

Mouse THRSP Affinity Purified Polyclonal Ab, Goat IgG - AF6574-SP from R&D Systems

Host Goat
Clonality Polyclonal
Detection of Mouse THRSP by Western Blot. Western blot shows lysates of mouse liver tissue. PVDF Membrane was probed with 0.5 µg/mL of Mouse THRSP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6574) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for THRSP at approximately 20 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

THRSP antibody - orb101720 from Biorbyt

Prices $60.00, $128.00, $255.00, $340.00
Sizes 5 μg (Trial Size), 20 μg (Trial Size), 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Immunofluorescence image of tongue squamous cell carcinoma using THRSP antibody.

THRSP Polyclonal Antibody - A7232 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cells, using THRSP antibody.

THRSP Antibody - abx005459 from Abbexa

Host Rabbit
Clonality Polyclonal
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