| Gene Symbol |
GPX2
|
| Entrez Gene |
2877
|
| Alt Symbol |
GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutathione peroxidase 2
|
| Other Description |
gastrointestinal glutathione peroxidase|glutathione peroxidase 2 (gastrointestinal)|glutathione peroxidase-related protein 2
|
| Swissprots |
Q6PJ52 Q9NRP9 P18283 Q8WWI7
|
| Accessions |
AAF74026 AAV31780 EAW80889 EAW80890 EAW80891 EAW80892 P18283 AK225871 BC005277 AAH05277 BC016756 AAH16756 BC022820 AAH22820 BC039850 BC046164 BC067221 AAH67221 BF207526 BG429974 X53463 CAB43534 X68314 CAA48394 NM_002083 NP_002074 NR_046320 NR_046321
|
| Function |
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
|
| Subcellular Location |
Cytoplasm. Note=Mainly cytoplasmic.
|
| Tissue Specificity |
Mostly in liver and gastrointestinal tract, not found in heart or kidney.
|
| Top Pathways |
Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism
|
![Western Blot: Glutathione Peroxidase 2 Overexpression Lysate (Adult Normal) [NBL1-11315] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Glutathione Peroxidase 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1554_Glutathione%2520Peroxidase%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11315-img0002.jpg)