BCCIP

Gene Symbol	BCCIP
Entrez Gene	56647
Alt Symbol	TOK-1, TOK1
Species	Human
Gene Type	protein-coding
Description	BRCA2 and CDKN1A interacting protein
Other Description	BCCIPalpha\|BCCIPbeta\|BRCA2 and CDKN1A-interacting protein\|BRCA2 and Cip1/p21 interacting protein\|TOK-1alpha\|TOK-1beta\|cdk inhibitor p21 binding protein\|p21- and CDK-associated protein 1\|protein TOK-1
Swissprots	Q96GC4 Q9P287 Q9P288 B3KP45 Q8ND15
Accessions	AAL55436 AAL55438 EAW49218 EAW49219 EAW49220 Q9P287 AA806484 AB040450 BAA92927 AB040451 BAA92928 AK055691 BAG51557 AK092054 AK300767 BAG62432 AK304529 BAG65330 AL834458 CAD39118 AY064248 AAL55439 AY064249 AAL55440 AY092061 BC009771 AAH09771 BM741863 BM905542 BM974496 BQ008485 NM_016567 NP_057651 NM_078468 NP_510868 NM_078469 NP_510869
Function	May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ). {ECO:0000269\|PubMed:10878006, ECO:0000269\|PubMed:14726710, ECO:0000269\|PubMed:15539944, ECO:0000269\|PubMed:15713648, ECO:0000269\|PubMed:17947333}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:10878006, ECO:0000269\|PubMed:11313963, ECO:0000269\|PubMed:15713648}. Note=Colocalizes with BRCA2 in discrete nuclear foci.
Tissue Specificity	Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen. {ECO:0000269\|PubMed:10878006, ECO:0000269\|PubMed:11313963}.

TOK-1 (13) - sc-136104 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	50 µg/0.5 ml
Host	Mouse
Clonality	Monoclonal

TOK-1 (13): sc-136104. Western blot analysis of TOK-1 expression in HeLa whole cell lysate.

TOK-1α (V-19) - sc-15414 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TOK-1β (B-10) - sc-271985 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

TOK-1β (B-10): sc-271985. Western blot analysis of TOK-1β expression in SK-BR-3 whole cell lysate.

TOK-1β (C-15) - sc-15417 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TOK-1β (C-15): sc-15417. Western blot analysis of TOK-1β expression in SK-BR-3 (A), Caki-1 (B), SW480 (C) and COLO 320DM (D) whole cell lysates.

Anti-BCCIP antibody - ab168157 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-BCCIP antibody (ab168157) at 1 µg/mlLane 1 : BCCIP transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgGdeveloped using the ECL technique

Anti-BCCIP antibody - ab97577 from Abcam

Prices	$304.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-BCCIP antibody (ab97577) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : HeLa whole cell lysateLysates/proteins at 30 µg per lane.

Anti-BCCIP antibody - ab177031 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon carcinoma tissue labeling BCCIP with ab177031 at 1/100 dilution.

Anti-BCCIP antibody - ab113288 from Abcam

Prices	$428.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ab113288, at 1/250 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human Colon Carcinoma by Immunohistochemistry with DAB staining.

Anti-BCCIP antibody - ab67119 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-BCCIP antibody (ab67119) at 1/500 dilutionLane 1 : BCCIP transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-BCCIP antibody - ab71473 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-BCCIP antibody (ab71473) at 1/100 dilution + A375 cell line lysate at 12.5 µgObserved band size : 33 kDa (why is the actual band size different from the predicted?)

Anti-BCCIP antibody - Carboxyterminal end - ab71453 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-BCCIP antibody - Carboxyterminal end (ab71453) at 1/60 dilution + A2058 cell line lysate at 12.5 µg

Anti-BCCIP Antibody (C-Terminus) - LS-C125207 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal

Anti-BCCIP Antibody (clone 2067C4a) - LS-C184687 from LifeSpan Bioscience

Prices	$335.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2067C4a

Anti-BCCIP Antibody (aa1-50) - LS-C288948 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BCCIP Antibody - LS-C306519 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-BCCIP Antibody (aa300-350) - LS-C288949 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human BCCIP by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BCCIP used at a dilution of 1:1000 (1 ug/ml).

Anti-BCCIP Antibody (clone 2067C4a) - LS-C342716 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2067C4a

Western blot analysis of immunized recombinant protein, using anti-BCCIP monoclonal antibody.

Anti-BCCIP Antibody (aa300-350) - LS-C286842 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human BCCIP by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-BCCIP used at a dilution of 1:100. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight 594 Conjugated (A120-601D4) used at a dilution of 1:100.

Anti-BCCIP Antibody (aa181-273) - LS-C186295 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

BCCIP antibody detects BCCIP protein at nucleus on U373 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U373 xenograft. BCCIP antibody dilution:1:500.

BCCIP Antibody - NBP1-22993 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: BCCIP Antibody [NBP1-22993] - Whole cell lysate from HeLa and 293T cells. BCCIP was also immunoprecipitated by rabbit anti-BCCIP antibody NBP1-22994.

BCCIP Antibody - NBP1-22994 from Novus Biologicals

Prices	$369.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunoprecipitation: BCCIP Antibody [NBP1-22994] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-BCCIP antibody used for IP at 3 mcg/mg lysate. BCCIP was also immunoprecipitated by rabbit anti- BCCIP antibody NBP1-22993, which recognizes an upstream epitope.

BCCIP Antibody - NBP1-31319 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

BCCIP Antibody - H00056647-B02P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: BCCIP Antibody [H00056647-B02P] - Analysis of BCCIP expression in transfected 293T cell line by BCCIP polyclonal antibody. Lane 1: BCCIP transfected lysate(35.42 KDa). Lane 2: Non-transfected lysate.

BCCIP Antibody - H00056647-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: BCCIP Antibody [H00056647-B01P] - Analysis of BCCIP expression in transfected 293T cell line by BCCIP polyclonal antibody. Lane 1: BCCIP transfected lysate(34.54 KDa). Lane 2: Non-transfected lysate.

BCCIP Antibody - H00056647-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: BCCIP Antibody [H00056647-B01] - analysis of BCCIP expression in transfected 293T cell line by BCCIP MaxPab polyclonal antibody (B01). Lane 1: BCCIP transfected lysate (34.54 KDa). Lane 2: Non-transfected lysate.

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