Gene Symbol | GNAI3 |
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Entrez Gene | 2773 |
Alt Symbol | 87U6, ARCND1 |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
Other Description | g(i) alpha-3|guanine nucleotide-binding protein G(k) subunit alpha |
Swissprots | P08754 P17539 Q5TZX1 |
Accessions | AAA35895 EAW56393 P08754 AF493907 AAM12621 AI684171 AK130069 AK311691 AK312252 BAG35184 AW984247 BC025285 AAH25285 BE886720 BI492787 BP289420 BT019973 AAV38776 BT019974 AAV38777 BU195094 BU622030 CX165017 DQ892862 ABM83788 DQ896111 ABM87110 J03005 AAA52557 J03198 AAA35896 J03238 AAA35939 M27543 AAA52579 NM_006496 NP_006487 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor- regulated K(+) channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division. {ECO:0000269|PubMed:17635935}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17635935}. Cell membrane {ECO:0000269|PubMed:17635935}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17635935}. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. |
Top Pathways | Circadian entrainment, Oxytocin signaling pathway, Estrogen signaling pathway, Adrenergic signaling in cardiomyocytes, Glutamatergic synapse |
Human GNAI3 full length protein - ab124586 from Abcam
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GNAI3 Recombinant Protein - H00002773-P01 from Novus Biologicals
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Recombinant Human GNAI3 Protein - NBP1-99039 from Novus Biologicals
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Human GNAI3 protein - orb244237 from Biorbyt
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Human GNAI3 protein - orb168416 from Biorbyt
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GNAI3 Blocking Peptide - 33R-9315 from Fitzgerald
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GNAI3 Blocking Peptide - 33R-2729 from Fitzgerald
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GNAI3 protein (His tag) - 80R-2227 from Fitzgerald
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G Protein alpha Inhibitor 3 (1-354, His-tag) - AR50311PU-N from Acris Antibodies
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G Protein alpha Inhibitor 3 (1-354, His-tag) - AR50311PU-S from Acris Antibodies
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G Protein alpha Inhibitor 3 - H00002773-P01-10 from Acris Antibodies
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G Protein alpha Inhibitor 3 - H00002773-P01-25 from Acris Antibodies
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GNAI3, 1-354aa, Human, His tag, E.coli - 01-P1486 from ARP American Research Products
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GNAI3 fusion protein - Ag2229 from Proteintech Group
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Recombinant Human GNAI3 Protein - BP001974-PRO-1074 from Syd Labs
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GNAI3, 1-354aa , Human, His tag, E.coli - GWB-P0552F from Genway Biotech
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Recombinant Human GNAI3 protein, His-tagged - GNAI3-382H from Creative Biomart
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Recombinant Human GNAI3 protein, MYC/DDK-tagged - GNAI3-380H from Creative Biomart
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Recombinant Human GNAI3 - GNAI3-226H from Creative Biomart
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Recombinant Human GNAI3, GST-tagged - GNAI3-13348H from Creative Biomart
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Recombinant G Protein Alpha Inhibiting Activity Polypeptide 3 (GNaI3) - RPJ014Hu01 from Uscn Life Science Inc.
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Recombinant Human Guanine nucleotide-binding protein G(k) subunit alpha(GNAI3) - CSB-YP009591HU CSB-BP009591HU CSB-MP009591HU from Cusabio
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Recombinant Human Guanine nucleotide-binding protein G(k) subunit alpha - CSB-EP009591HU from Cusabio
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GNAI3, 1-354aa, Human, His tag, E.coli - ATGP1486 from ATGen
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GNAI3 Peptide - abx164596 from Abbexa
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