| Gene Symbol |
GRB2
|
| Entrez Gene |
2885
|
| Alt Symbol |
ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
growth factor receptor-bound protein 2
|
| Other Description |
HT027|SH2/SH3 adapter GRB2|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3|protein Ash
|
| Swissprots |
P62993
|
| Accessions |
AAC72075 ABY87532 AGC09591 EAW89270 EAW89271 EAW89272 P62993 AA452034 AF171699 AAQ13606 AF246238 AAG44485 AF302079 AAG27442 AF498925 AAM21073 AK024539 BAB14923 AK091010 BAG52262 AK315565 BAG37940 BC000631 AAH00631 BC019082 BC033644 BC039827 BC043007 BI459414 BQ073225 BQ962129 CR450363 CAG29359 CR541942 CAG46740 DA458680 DQ891830 ABM82756 DQ894923 ABM85849 L29511 AAC37549 M96995 AAA58448 X62852 CAA44664 NM_002086 NP_002077 NM_203506 NP_987102
|
| Function |
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21179510}. Cytoplasm {ECO:0000269|PubMed:21179510}. Endosome {ECO:0000269|PubMed:21179510}. Golgi apparatus {ECO:0000250}.
|
| Top Pathways |
MicroRNAs in cancer, Prolactin signaling pathway, Estrogen signaling pathway, Alcoholism, Signaling pathways regulating pluripotency of stem cells
|
![Western Blot: GRB2 Overexpression Lysate (Adult Normal) [NBL1-11326] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GRB2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8719_GRB2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11326-img0002.jpg)