GRB2

Gene Symbol GRB2
Entrez Gene 2885
Alt Symbol ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
Species Human
Gene Type protein-coding
Description growth factor receptor-bound protein 2
Other Description HT027|SH2/SH3 adapter GRB2|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3|protein Ash
Swissprots P62993
Accessions AAC72075 ABY87532 AGC09591 EAW89270 EAW89271 EAW89272 P62993 AA452034 AF171699 AAQ13606 AF246238 AAG44485 AF302079 AAG27442 AF498925 AAM21073 AK024539 BAB14923 AK091010 BAG52262 AK315565 BAG37940 BC000631 AAH00631 BC019082 BC033644 BC039827 BC043007 BI459414 BQ073225 BQ962129 CR450363 CAG29359 CR541942 CAG46740 DA458680 DQ891830 ABM82756 DQ894923 ABM85849 L29511 AAC37549 M96995 AAA58448 X62852 CAA44664 NM_002086 NP_002077 NM_203506 NP_987102
Function Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Subcellular Location Nucleus {ECO:0000269|PubMed:21179510}. Cytoplasm {ECO:0000269|PubMed:21179510}. Endosome {ECO:0000269|PubMed:21179510}. Golgi apparatus {ECO:0000250}.
Top Pathways MicroRNAs in cancer, Prolactin signaling pathway, Estrogen signaling pathway, Alcoholism, Signaling pathways regulating pluripotency of stem cells

SignalSilence ® GRB2 siRNA I - 13265 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from 293T cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® GRB2 siRNA I (+), using GRB2 Antibody #3972 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The GRB2 Antibody confirms silencing of GRB2 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

GRB2 CRISPR/Cas9 KO Plasmid (h) - sc-400482 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 HDR Plasmid (h) - sc-400482-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 Double Nickase Plasmid (h) - sc-400482-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 Double Nickase Plasmid (h2) - sc-400482-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 CRISPR Activation Plasmid (h) - sc-400482-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 CRISPR Activation Plasmid (h2) - sc-400482-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 Lentiviral Activation Particles (h) - sc-400482-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 Lentiviral Activation Particles (h2) - sc-400482-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRB2 siRNA (h) - sc-29334 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GRB2 shRNA Plasmid (h) - sc-29334-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GRB2 shRNA (h) Lentiviral Particles - sc-29334-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU091241 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9665 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9665 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11197 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11197

GRB2 siRNA (Human) - CRH1939 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRB2 RNAi - H00002885-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GRB2 RNAi - H00002885-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GRB2 - MBS8233626 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GRB2 (NM_002086.4) - SHH307590 from Creative biogene

Category siRNA
Species Reactivities Human

GRB2 shRNA Plasmid (Human) - CHH1939 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GRB2 miRNA 3'UTR clone - MiUTR1H-04252 from Creative biogene

Species Reactivities Human

GRB2 miRNA 3'UTR clone - MiUTR1H-04253 from Creative biogene

Species Reactivities Human
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