GRB2

Gene Symbol GRB2
Entrez Gene 2885
Alt Symbol ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
Species Human
Gene Type protein-coding
Description growth factor receptor-bound protein 2
Other Description HT027|SH2/SH3 adapter GRB2|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3|protein Ash
Swissprots P62993
Accessions AAC72075 ABY87532 AGC09591 EAW89270 EAW89271 EAW89272 P62993 AA452034 AF171699 AAQ13606 AF246238 AAG44485 AF302079 AAG27442 AF498925 AAM21073 AK024539 BAB14923 AK091010 BAG52262 AK315565 BAG37940 BC000631 AAH00631 BC019082 BC033644 BC039827 BC043007 BI459414 BQ073225 BQ962129 CR450363 CAG29359 CR541942 CAG46740 DA458680 DQ891830 ABM82756 DQ894923 ABM85849 L29511 AAC37549 M96995 AAA58448 X62852 CAA44664 NM_002086 NP_002077 NM_203506 NP_987102
Function Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Subcellular Location Nucleus {ECO:0000269|PubMed:21179510}. Cytoplasm {ECO:0000269|PubMed:21179510}. Endosome {ECO:0000269|PubMed:21179510}. Golgi apparatus {ECO:0000250}.
Top Pathways MicroRNAs in cancer, Prolactin signaling pathway, Estrogen signaling pathway, Alcoholism, Signaling pathways regulating pluripotency of stem cells

GRB2 Antibody - 3972 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, A431, HEK293, Ramos, NIH/3T3, C6, COS, CHO and BAEC cells, using GRB2 Antibody.

GRB2 (C-6) - sc-365619 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GRB2 (C-6): sc-365619. Western blot analysis of Bcl-6 expression in A-431 whole cell lysate.

GRB2 (C-23) - sc-255 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GRB2 (C-23): sc-255. Western blot analysis of GRB2 expression in PC-12 (A) and KNRK (B) whole cell lysates.

GRB2 (1-68) - sc-503 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of GRB2 expression in Jurkat immunoprecipitated with GRB2 (1-68): sc-503 and detected with GRB2 (G-23): sc-255.

GRB2 (C-7) - sc-8034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GRB2 (C-7): sc-8034. Immunofluorescence staining of methanol-fixed KNRK cells showing membrane staining.

GRB2 (E-1) - sc-17813 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GRB2 (E-1): sc-17813. Western blot analysis of GRB2 expression in COLO 320DM (A), PC-12 (B), KNRK (C) and NIH/3T3 (D) whole cell extracts.

GRB2 (F-3) - sc-137074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GRB2 (F-3): sc-137074. Western blot analysis of GRB2 expression in COLO 320DM (A), A-431 (B), PC-12 (C), NIH/3T3 (D) and KNRK (E) whole cell lysates.

GRB2 (H-68) - sc-28839 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GRB2 (H-68): sc-28839. Western blot analysis of GRB2 expression in PC-12 whole cell lysate.

GRB2 (H-70) - sc-13953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GRB2 (H-70): sc-13953. Western blot analysis of GRB2 expression in COLO 320DM (A) and A-431 (B) whole cell lysates.

GRB2 (H-9) - sc-137056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GRB2 (H-9): sc-137056. Western blot analysis of GRB2 expression in PC-12 (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.

Anti-GRB2 + Lamin B Receptor antibody [Y237] (HRP) - ab201865 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y237
Anti-GRB2 + Lamin B Receptor antibody [Y237] (HRP) (ab201865) at 1/5000 dilution + HEK293 (Human embryonic kidney cell line) Whole Cell Lysa at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-GRB2 antibody - ab111031 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab111031, at 10µg/ml, staining GRB2 in Formalin-fixed, Paraffin-embedded Human Brain cerebellum tissue by Immunohistochemistry.

Anti-GRB2 antibody - ab109651 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-GRB2 antibody (ab109651) at 2 µg/ml + Jurkat lysate at 35 µgdeveloped using the ECL technique

Anti-GRB2 antibody - ab79876 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GRB2 antibody (ab79876) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 4 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLane 5 : Ramos (Human Burkitt's lymphoma cell line) Whole Cell LysateLane 6 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-GRB2 antibody - ab2234 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-GRB2 antibody (ab2234) at 2 µg/ml + Jurkat lysate (RIPA buffer, 35µg total protein per lane).

Anti-GRB2 antibody - ab14299 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-GRB2 antibody - ab65117 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GRB2 antibody (ab65117) at 1/50 dilutionLane 1 : 293 cell lysates, nontransfected Lane 2 : 293 cell lysates, transiently transfected with the GRB2 gene Lysates/proteins at 2 µg per lane.

Anti-GRB2 antibody [2GB04] - ab140351 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone 2GB04

Anti-GRB2 antibody [GRB-232] - ab49876 from Abcam

Prices $375.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GRB-232

Anti-GRB2 antibody [M331] - ab86713 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone M331
Lane 1 : Anti-GRB2 antibody [M331] (ab86713) at 1/250 dilutionLane 2 : Anti-GRB2 antibody [M331] (ab86713) at 1/500 dilutionLane 3 : Anti-GRB2 antibody [M331] (ab86713) at 1/1000 dilutionLane 1 : PC12 cell lysateLane 2 : PC12 cell lysateLane 3 : PC12 cell lysateObserved band size : 24 kDa (why is the actual band size different from the predicted?)

Anti-GRB2 antibody, prediluted - ab26402 from Abcam

Host Mouse
Clonality Monoclonal
Ab26402 (neat) staining GRB2 in formalin/paraffin fixed human tonsil tissue by Immunohistochemical staining.

Anti-GRB2 antibody [R11] - ab232 from Abcam

Prices $359.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone R11

Anti-GRB2 antibody [Y237] - ab32037 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone Y237
Anti-GRB2 antibody [Y237] (ab32037) at 1/10000 dilution + 293 cell lysate

Anti-GRB2 antibody [Y301] - ab32111 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y301
All lanes : Anti-GRB2 antibody [Y301] (ab32111) at 1/2000 dilutionLane 1 : NIH 3T3 cell lysateLane 2 : PC12 cell lysateLane 3 : HeLa cell lysate

Anti-GRB2 antibody - N-terminal - ab80065 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GRB2 antibody - N-terminal (ab80065) at 1/50 dilution + HepG2 cell line lysate at 35 µg
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