Gene Symbol | NRAS |
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Entrez Gene | 4893 |
Alt Symbol | ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6 |
Species | Human |
Gene Type | protein-coding |
Description | neuroblastoma RAS viral (v-ras) oncogene homolog |
Other Description | GTPase NRas|N-ras protein part 4|transforming protein N-Ras|v-ras neuroblastoma RAS viral oncogene homolog |
Swissprots | Q14971 Q15104 Q15282 P01111 |
Accessions | AAA36548 AAA36556 AAA60255 AAB29639 AAQ94397 ABY87546 CAA25269 CAA25270 CAA25271 CAA25272 CAA29078 CAA29079 CAA30320 CAA37384 CBV35642 CDL93481 EAW56608 EAW56609 EAW56610 EAW56611 P01111 AF493919 AAM12633 AW021410 AY941100 AY941101 BC005219 AAH05219 BC013214 BT019734 AAV38539 BT019735 AAV38540 DA007844 X02751 CAA26529 NM_002524 NP_002515 |
Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15705808}; Lipid-anchor {ECO:0000269|PubMed:15705808}; Cytoplasmic side {ECO:0000269|PubMed:15705808}. Golgi apparatus membrane {ECO:0000269|PubMed:15705808}; Lipid-anchor {ECO:0000269|PubMed:15705808}. Note=Shuttles between the plasma membrane and the Golgi apparatus. |
Top Pathways | Sphingolipid signaling pathway, Axon guidance, PI3K-Akt signaling pathway, Rap1 signaling pathway, Choline metabolism in cancer |
N-Ras (C-20) - sc-519 from Santa Cruz Biotechnology
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N-Ras (F155) - sc-31 from Santa Cruz Biotechnology
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N-Ras (R-16) - sc-32028 from Santa Cruz Biotechnology
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pan Ras (C-4) - sc-166691 from Santa Cruz Biotechnology
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pan Ras (FL-189) - sc-14022 from Santa Cruz Biotechnology
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Anti-NRAS antibody [AT2G9] - ab113627 from Abcam
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Anti-NRAS antibody - C-terminal - ab198820 from Abcam
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Anti-NRAS antibody - C-terminal - ab167136 from Abcam
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Anti-NRAS / N-ras Antibody (clone 2A3) - LS-C197802 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (aa91-140) IHC-plus⢠- LS-B8261 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (Effector Region, clone Y131) - LS-C49527 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (clone SP174) - LS-C210402 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (Q61R mutation, clone RBT-NRAS) - LS-C348548 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (clone RBT-NRAS, Ready-to-Use) - LS-C348547 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (clone 5G7) - LS-C174539 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (aa70-101, clone 822CT17.5.1) - LS-C344579 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (clone AT2G9) IHC-plus⢠- LS-B6270 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (aa147-179) - LS-C99435 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (aa72-101) - LS-C99434 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (N-Terminus, clone EP1125Y) IHC-plus™ - LS-B6126 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (aa167-179) IHC-plus⢠- LS-B2501 from LifeSpan Bioscience
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Anti-NRAS / N-ras Antibody (C-Terminus) IHC-plus⢠- LS-B10113 from LifeSpan Bioscience
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NRAS Antibody (EP1125Y) - NB100-80042 from Novus Biologicals
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NRAS Antibody - NB100-94887 from Novus Biologicals
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KRAS Antibody - NBP1-58261 from Novus Biologicals
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